1例食源性单核增生性李斯特菌败血症和脑膜炎导致严重脑积水  

A Case Study of Severe Hydrocephalus Caused by Listeria Monocytogenes Septicemia and Meningitis

作　　者：卢兴兵[1] 戴仲秋 谢轶[1] LU Xingbing;DAI Zhongqiu;XIE Yi(Department of Laboratory Medicine,West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院实验医学科,四川成都610041

出　　处：《标记免疫分析与临床》2020年第10期1831-1835,共5页Labeled Immunoassays and Clinical Medicine

摘　　要：单核细胞增生性李斯特菌是导致严重食源性疾病的病原体之一。常发生于新生儿、孕妇和老年人,以及免疫受损等高危人群,常引起脓毒血症和脑膜炎。本文患者女,71岁,由于食用被单核增生性李斯特菌污染的食品而感染,发生败血症和脑膜炎双重感染,出现头痛、寒战、发热,予以“头孢曲松”经验性抗感染治疗无效。尽管患者接受了积极的脑室外引流,仍意识障碍、昏迷,颅内散在缺血脑梗灶,脑萎缩、水肿加重,颅内压增高,病情加重恶化,最终救治无效死亡。Listeria monocytogenes is one of the pathogens that causes serious foodborne diseases.It often occurs among newborns,pregnant women and the elderly populations,as well as high-risk groups such as immune impairment patients,often causing sepsis and meningitis.In this paper,a 71-year old woman was infected by Listeria monocytogenes contaminated food.She suffered from both septicemia and meningitis,with symptoms of headache,shiver and fever.The treatment of ceftriaxone was ineffective.Although the patient received the.positive ventricular drainage,still had conscious disturbance,coma,intracranial scattered ischemic cerebral infarction,brain atrophy,edema,increased intracranial pressure,and aggravation of the disease.The final treatment was invalid and the patient died.

关 键 词：食源性 李斯特菌 败血症 脑膜炎 脑积水 

分 类 号：R631.3[医药卫生—外科学]