Astrocytic role of Thy-1 induced inhibition of axonal sprouting  

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作  者:Sara T.Whiteman Jason M.Askvig 

机构地区:[1]Department of Biology,Concordia College,Moorhead,MN,USA

出  处:《Neural Regeneration Research》2021年第6期1192-1193,共2页中国神经再生研究(英文版)

摘  要:Thy-1 as an“anti-sprouting”factor:Since the identification of Thy-1(CD-90)in 1964 by Reif and Allen,the precise functions of this glycosyl phosphatidylinositol-anchored surface protein within the central nervous system have been difficult to characterize.Thy-1 is a 110-amino acid cellular adhesion molecule that plays a role in cell-cell communication by interacting with other cellular adhesion molecules,including integrins(Leyton et al.,2001).While found on a diverse array of cells within the body,Thy-1 is present on the surface of almost every neuron in the brain(Morris and Grosveld,1989).

关 键 词:PRECISE system INTERACTING 

分 类 号:R741[医药卫生—神经病学与精神病学]

 

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