Analysis of 234 cases of colorectal polyps treated by endoscopic mucosal resection  

作　　者：Lu Yu Na Li Xiao-Mei Zhang Tao Wang Wei Chen 

机构地区：[1]Department of Gastroenterology,Maanshan Central Hospital,Maanshan 243000,Anhui Province,China [2]Department of Gastroenterology,Affiliated Hospital of Southeast University,Nanjing 210009,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2020年第21期5180-5187,共8页世界临床病例杂志

摘　　要：BACKGROUND Colorectal polyps refer to all neoplasms that protrude into the intestinal cavity.Researchers believe that 50%-70%of colorectal cancers originate from adenomatous polyps.AIM To investigate the endoscopic morphologic features,pathologic types,and clinical situation;evaluate the efficacy and safety of endoscopic mucosal resection(EMR);and guide clinicians in their daily practice.METHODS Two hundred thirty-four patients who underwent EMR in our hospital from January 1,2018 to December 31,2019 were recruited.Data including sex,age,endoscopic morphology of the polyps,and pathological characteristics were analyzed among groups.RESULTS A total of 295 polyps were resected from the 234 subjects enrolled in the study,of which 4(1.36%)were Yamada type I.There were 75(25.42%)type II,101(34.24%)type III,and 115(38.98%)type IV adenomas.Among them,41 were nonadenomas,110 were low-risk adenomas,139 were high-risk adenomas,and 5 were carcinomas.The differences in distribution were not statistically significant,with P values greater than 0.05.The risk of cancer significantly increased for polyps≥1 cm in diameter(c2=199.825,P=0.00).Regarding the endoscopic morphological features,congestion,erosion,and lobulation were more common on the surface morphology of high-risk adenomas and cancerous polyps(c2=75.257,P=0.00),and most of them were Yamada types III and IV.In all,6 of the 295 polyps could not be removed completely,with a one-time resection rate of 97.97%.There were two cases of postoperative bleeding and no cases of perforation,with an overall complication rate of 0.09%.CONCLUSION Colorectal polyps ranging from non-adenomatous polyps,low-risk adenomas,and high-risk adenomas to adenocarcinomas each has their own endoscopic features,while EMR,as a mature intervention,has good safety and operability and should be promoted clinically,especially at the primary care level.

关 键 词：Colorectal polyp Endoscopic mucosal resection High-risk adenoma Risk factors ADENOCARCINOMAS 1 4-bis(diphenylphosphino)butane 

分 类 号：R735.34[医药卫生—肿瘤]