溃疡性结肠炎患者合并焦虑和抑郁状态的影响因素分析  

Influencing factors of anxiety and depression in patients with ulcerative colitis

作　　者：南楠 李卉[1] 田丰[1] NAN Nan;LI Hui;TIAN Feng(Department of Gastroenterology,Shengjing Hospital Affiliated to China Medical University,Shenyang 110004,China;不详)

机构地区：[1]中国医科大学附属盛京医院消化内科,辽宁沈阳110004

出　　处：《中国实用内科杂志》2020年第10期832-835,共4页Chinese Journal of Practical Internal Medicine

摘　　要：目的探讨溃疡性结肠炎(UC)患者合并焦虑和抑郁状态的影响因素。方法招募在2015年1月至2019年7月期间于中国医科大学附属盛京医院住院诊治的UC患者,对同意入组且符合条件的UC患者进行问卷调查,运用SPSS 25.0软件进行统计学分析。结果共获得72例UC患者完整资料。其中,27例(37.50%)合并焦虑状态,26例(36.11%)合并抑郁状态,20例(27.78%)同时合并焦虑和抑郁状态。高压力(OR 29.51,95%CI 3.84~227.11,P=0.001)及疾病活动(OR 12.62,95%CI 2.08~76.68,P=0.006)是UC患者合并焦虑状态的危险因素,疾病活动(OR 4.04,95%CI0.09~18.15,P=0.073)可能是UC患者合并抑郁的危险因素。结论处于疾病活动期、高压力状态的UC患者更易合并焦虑及抑郁状态。Objective To explore the factors associated with anxiety and depression in patients with ulcerative colitis(UC).Methods Recruiting the patients with UC who were hospitalized in Shengjing Hospital from January 2015 to July 2019.Data were collected viaquestionnaires andanalyses were performed by SPSS 25.0.Results Seventy-two patients completed all the investigations.Among them,27 patients(37.50%)had anxious symptoms and 26 patients(36.11%)had depressive symptoms,and 20 patients(27.78%)were not only anxious but also depressive.The risk factors associated with anxiety are high stress(OR 29.51,95%CI 3.84~227.11,P=0.001),and active disease(OR 12.62,95%CI 2.08~76.68,P=0.006).Active disease(OR 4.04,95%CI 0.09~18.15,P=0.073)trended toward an association with depression although it was not statistically significant.Conclusion Being in active disease,and having high stress are more likely to be anxious or depressive.

关 键 词：溃疡性结肠炎 焦虑 抑郁 

分 类 号：R574[医药卫生—消化系统]