核酸适体在乳及乳制品检测中的应用  

A Review on Recent Advances in Application of Aptamers in the Detection of Milk and Dairy Products

作　　者：张亚丽 牛立沙 赵丽敏 范素芳[1] 黄云霞 张岩[1] 范斌[1] ZHANG Yali;NIU Lisha;ZHAO Limin;FAN Sufang;HUANG Yunxia;ZHANG Yan;FAN Bin(Hebei Food Inspection and Research Institute,Hebei Key Laboratory of Food Safety,Shijiazhuang 050227,China)

机构地区：[1]河北省食品安全重点实验室,河北省食品检验研究院,河北石家庄050227

出　　处：《乳业科学与技术》2020年第5期43-48,共6页JOURNAL OF DAIRY SCIENCE AND TECHNOLOGY

基　　金：“十三五”国家重点研发计划重点专项(2018YFC1603400);河北省高层次人才资助项目(A2017005008)。

摘　　要：核酸适体技术是新型检测技术,因其特异性、高亲和性、快速、低成本等众多优点被广泛应用于乳及乳制品等动物源食品安全检测领域。本文对核酸适体筛选技术的原理和类别进行介绍,并对其在乳及乳制品中添加剂、激素、抗生素残留、真菌毒素、病原微生物污染检测等方面的应用和研究进展进行综述。Aptamer technology is a new detection technology which has been widely used in the field of animal-origin food safety detection because of its specificity,high affinity,rapidity and low cost.In this paper,we describe the principle and classification of aptamer screening technologies,and we review recent progress in their applications in the detection of food additives,veterinary drug,hormone and antibiotic residues,mycotoxins,and pathogenic bacteria in milk and dairy products.

关 键 词：核酸适体 乳及乳制品 检测 

分 类 号：TS252.1[轻工技术与工程—农产品加工及贮藏工程]