促肾上腺皮质激素型垂体腺瘤的发病机制及诊疗进展  

Advances in pathogenesis,diagnosis and treatment of adrenocorticotropic pituitary adenomas

作　　者：王志涛[1] 张川[1] Wang Zhitao;Zhang Chuan(Department of Neurosurgery,Tianjin Medical University General Hospital,Tianjin 300052,China)

机构地区：[1]天津医科大学总医院神经外科,天津300052

出　　处：《中华脑科疾病与康复杂志（电子版）》2020年第2期120-122,共3页Chinese Journal of Brain Diseases and Rehabilitation（Electronic Edition）

摘　　要：促肾上腺皮质激素型垂体腺瘤又称库欣病(CD),由垂体肿瘤自主分泌促肾上腺皮质激素导致肾上腺分泌过多的皮质醇所引起。阐明CD的发病机制有助于诊断和治疗该疾病,对于改善患者的临床表现以及预后评估也有着重要意义。本文通过复习文献对CD的发病机制和诊疗研究进展进行综述。Adrenocorticotropic pituitary adenomas,also known as Cushing’s disease(CD),is caused by the autonomic secretion of adrenocorticotropic hormone by pituitary tumor,which leads to the excessive secretion of cortisol by adrenal gland.To clarify the pathogenesis of CD is helpful for diagnosis and treatment of the disease,and it is also of great significance for improving the clinical performance and prognosis evaluation of patients.This article reviews the literature on the pathogenesis and diagnosis and treatment of CD.

关 键 词：库欣病 垂体 促肾上腺皮质激素 发病机制 

分 类 号：R736.4[医药卫生—肿瘤]