腹腔穿刺与腹腔输液港在卵巢癌患者腹腔化疗中的应用比较  

Comparison of the application of abdominocentesis and intraperitoneal port in intraperitoneal chemotherapy for ovarian cancer patients

作　　者：张天[1] 林梦[1] 何悦[1] 潘凌亚[2] 王涛[2] 付晨薇[1] ZHANG Tian;LIN Meng;HE Yue;PAN Lingya;WANG Tao;FU Chenwei(International Medical Department Peking Union Medical College Hospital,Beijing 100730,China;Department of Gynecology,Peking Union Medical College Hospital,Beijing 100730,China)

机构地区：[1]北京协和医院国际医疗部,北京100730 [2]北京协和医院妇产科,北京100730

出　　处：《现代肿瘤医学》2020年第23期4136-4141,共6页Journal of Modern Oncology

基　　金：北京协和医院院内课题(编号:XHHLKY201815)。

摘　　要：目的:探讨腹腔穿刺与腹腔输液港在卵巢癌患者腹腔化疗中的应用效果。方法:选择2017年1月至2018年12月住院行腹腔化疗的卵巢癌患者90例,其中腹腔穿刺组患者45例,腹腔输液港组患者45例。对比2组患者的治疗效果、导管相关并发症发生情况、穿刺时疼痛评分、一次性穿刺成功率以及疗程完成情况。结果:两组患者治疗效果比较差异无统计学意义(P>0.05);导管相关并发症发生情况,两组比较差异无统计学意义(P>0.05);腹腔输液港组患者穿刺疼痛评分低于腹腔穿刺组,两组M(P25,P75)评分分别为2.00(1.40,2.50)和5.33(5.00,5.67),差异具有统计学意义(P<0.05),腹腔输液港组患者有18例主诉在留置期间存在腹部异物感;腹腔穿刺组患者一次性穿刺成功率为87.44%(181/207),腹腔输液港组患者为95.04%(249/262),两组比较差异具有统计学意义(P<0.05);腹腔穿刺组患者疗程完成率为82.22%(37/45),腹腔输液港组为95.56%(43/45),差异具有统计学意义(P<0.05)。结论:腹腔输液港相较于腹腔穿刺应用于腹腔化疗中,其一次性穿刺成功率更高,疗程完成度更好,故在经济条件允许且化疗周期较长、腹部穿刺困难或对疼痛不耐受的患者可考虑置入腹腔输液港。Objective:To explore the application effect of abdominocentesis and intraperitoneal port in intraperitoneal chemotherapy for ovarian cancer patients.Methods:From January 2017 to December 2018,90 patients with ovarian cancer who underwent intraperitoneal chemotherapy were selected,including 45 patients in abdominocentesis group and 45 patients in intraperitoneal port group.The treatment effect,occurrence of catheter-related complications,pain score during puncture,success rate of one-time puncture and completion of treatment course were compared between the two groups.Results:There was no statistically significant difference in treatment effect between the two groups(P>0.05).There was no significant difference in catheter-related complications between the two groups(P>0.05).The puncture pain score of patients in the intraperitoneal infusion port group was lower than that in the abdominocentesis group.The M(P25,P75) scores of the two groups were 2.00(1.40,2.50) and 5.33(5.00,5.67),and the difference was statistically significant(P<0.05).18 patients in the intraperitoneal port group complained of abdominal foreign body sensation during retention.The success rate of one-time puncture was 87.44%(181/207) in the abdominocentesis group and 95.04%(249/262) in the intraperitoneal port group.The difference between the two groups was statistically significant(P<0.05).The treatment course completion rate of patients in the abdominocentesis group was 82.22%(37/45),and that in the intraperitoneal port group was 95.56%(43/45),with statistically significant difference(P<0.05).Conclusion:Compared with the application of abdominocentesis in intraperitoneal chemotherapy,intraperitoneal port has higher success rate of one-time puncture and better completion of treatment course.Therefore,patients with economic conditions permitting,longer chemotherapy period,difficult abdominal puncture or intolerance to pain can be considered to be placed in intraperitoneal port.

关 键 词：卵巢癌 腹腔穿刺 腹腔输液港 腹腔化疗 

分 类 号：R737.31[医药卫生—肿瘤]