Application of flavonoids for the protection of nigral dopaminergic neurons from oxidative stress  

作　　者：Sang Ryong Kim 

机构地区：[1]School of Life Sciences,BK21 plus KNU Creative BioResearch Group/Institute of Life Science&Biotechnology/Brain Science and Engineering Institute,Kyungpook National University,Daegu,Korea

出　　处：《Neural Regeneration Research》2021年第7期1409-1410,共2页中国神经再生研究（英文版）

基　　金：supported by a grant from the National Research Foundation of Korea, No.NRF-2020R1A2C2007954(to SRK)。

摘　　要：Oxidative stress in Parkinson's disease(PD): Oxidative stress is the imbalance between oxidants, which generate reactive oxygen species(ROS;free radicals), and antioxidants, which remove free radicals.Under healthy conditions, the levels of oxidants and antioxidants are wellbalanced.However, excessive production of ROS and a deficiency of antioxidants leads to oxidative stress, which may be the cause of accelerating the development of neurodegenerative diseases(Hwang, 2013), suggesting that the prevention of ROS production and reduction of oxidative stress is critical for both the prevention and treatment of neurodegenerative diseases, including PD.

关 键 词：PREVENTION REMOVE OXIDATIVE 

分 类 号：R742.5[医药卫生—神经病学与精神病学]