多发腔隙性脑梗死不同时期脑血管功能变化  

Changes of cerebrovascular function in different stages of multiple lacunar infarction

作　　者：黄达 HUANG Da(Department of Neurology,Shenyang Fourth People′s Hospital,Liaoning Province,Shenyang110031,China)

机构地区：[1]沈阳市第四人民医院神经内科,辽宁沈阳110031

出　　处：《中国当代医药》2020年第32期105-107,共3页China Modern Medicine

摘　　要：目的观察多发腔隙性脑梗死不同时期的脑血管功能变化。方法随机选取2017年8月~2018年8月沈阳市第四人民医院的100例多发腔隙性脑梗死患者,依据疾病类型分为急性组(50例)与慢性组(50例),另随机选取沈阳市第四人民医院同期的50例有脑血管危险因素的患者作为对照组,同时随机选取沈阳市第四人民医院同期的50名健康体检人员作为健康组,统计分析四组的最小血流速度(Vmin)、平均血流速度(Vmean)、平均血流量(Qmean)、脉搏波速(WV)、脑血管特性阻抗(Zcv)、脑血管外周阻力(Rv)、动态阻力(DR)、临床压力(CP)。结果急性组患者的Vmin、Vmean均低于慢性组、对照组、健康组(P<0.05),Zcv、DR均高于慢性组、对照组、健康组(P<0.05);而慢性组、对照组患者的Vmin、Vmean均低于健康组(P<0.05),Zcv、DR均高于健康组(P<0.05);但慢性组和对照组患者的Vmin、Vmean、Zcv、DR比较,差异无统计学意义(P>0.05)。急性组患者的Qmean低于慢性组、对照组、健康组(P<0.05),CP高于慢性组、对照组、健康组(P<0.05);而慢性组患者的Qmean低于对照组、健康组(P<0.05),CP高于对照组、健康组(P<0.05);但对照组和健康组人员的Qmean、CP比较,差异无统计学意义(P>0.05);急性组、慢性组、对照组患者的WV均高于健康组(P<0.05),但急性组、慢性组、对照组患者的WV比较,差异无统计学意义(P>0.05);急性组、慢性组、对照组、健康组人员的WV逐渐降低。结论多发腔隙性脑梗死急性期、慢性期、梗死前的脑血管功能逐渐降低。Objective To observe the changes of cerebrovascular function in different stages of multiple lacunar infarction.Methods A total of 100 patients with multiple lacunar infarction from August 2017 to August 2018 in Shenyang Fourth People′s Hospital were randomly selected,and they were divided into the acute group(50 cases)and the chronic group(50 cases)according to the types of disease.Another 50 patients with cerebrovascular risk factors in Shenyang Fourth People′s Hospital during the same period were randomly selected as the control group.Another 50 health examinees in Shenyang Fourth People′s Hospital during the same period were randomly selected as the health group.The Minimum blood flow velocity(Vmin),average blood flow velocity(Vmean),average blood flow(Qmean),pulse wave velocity(WV),cerebrovascular characteristic impedance(Zcv),cerebrovascular peripheral resistance(Rv),dynamic resistance(DR),clinical stress(CP)of the four groups were statistically analyzed.Results The Vmin and Vmean of patients in the acute group were lower than those of the chronic group,the control group and the healthy group(P<0.05),Zcv and DR in the acute group were higher than those of the chronic group,the control group and the healthy group(P<0.05).The Vmin and Vmean of the chronic group and the control group were lower than that of the healthy group(P<0.05),and the Zcv and DR of the chronic group and the control group were higher than those of the healthy group(P<0.05).However,there were no significant differences in Vmin,Vmean,Zcv,DR between the chronic group and the control group(P>0.05).The Qmean of patients in the acute group were lower than those of the chronic group,the control group and the healthy group(P<0.05),CP in the acute group were higher than those of the chronic group,the control group and the healthy group(P<0.05),and the Qmean of patients in the chronic group were lower than those of the control group and the healthy group(P<0.05),CP in the chronic group were higher than those of the control group and the healt

关 键 词：多发腔隙性脑梗死 急性期 慢性期 脑血管功能变化 

分 类 号：R743.3[医药卫生—神经病学与精神病学]