原发性十二指肠癌的临床诊治进展  

Clinical diagnosis and treatment progress of primary duodenal cancer

作　　者：耿证琴 谢琳 李蓉 廖冶丹 周灵 唐嘉黛 张雪琪 Geng Zhengqin;Xie Lin;Li Rong;Liao Yedan;Zhou Ling;Tang Jiadai;Zhang Xueqi(Department of Digestive Oncology Internal Medicine,the Third Affiliated Hospital of Kunming Medical University,Tumor Hospital of Yunnan Province,Kunming 650118,China)

机构地区：[1]云南省肿瘤医院,昆明医科大学第三附属医院消化肿瘤内科,昆明650118

出　　处：《肿瘤研究与临床》2020年第10期730-733,共4页Cancer Research and Clinic

基　　金：国家自然科学基金(81760520/H1606)。

摘　　要：十二指肠癌是较为少见的消化道恶性肿瘤,早期症状缺乏特异性,临床上诊断困难,容易被误诊、漏诊。十二指肠癌治疗以手术为主,放化疗为辅,大部分患者初诊时就已经发生局部侵犯或远处转移,缺乏有效的治疗方法,预后极差。近年来研究指出靶向治疗和免疫治疗可改善十二指肠癌患者的预后。现对十二指肠癌的诊治进展进行综述,希望对指导临床诊疗和研发新的治疗方案有所帮助。Duodenal cancer is a clinically rare gastrointestinal malignant tumor.Its early symptoms lack specificity,making it difficult to diagnose clinically and easy to be misdiagnosed and missed.The treatment of duodenal cancer is mainly surgery,supplemented by radiotherapy and chemotherapy.Most patients have already experienced local invasion or distant metastasis at the time of first diagnosis,and lack of effective treatment,the prognosis is extremely poor.In recent years,a series of studies have pointed out that targeted therapy and immunotherapy can improve the prognosis of patients with duodenal cancer.This article reviews the progress of diagnosis and treatment of duodenal cancer,hoping to help guide clinical diagnosis and treatment and develop new treatment options.

关 键 词：十二指肠肿瘤 诊断 治疗 预后 

分 类 号：R735.31[医药卫生—肿瘤]