分期治疗眼部碱烧伤的临床观察  

Clinical observation on the treatment of ocular alkali burn by stages

作　　者：惠玲 程燕 宋金鑫 吴洁[1] 朱海峰 Ling Hui;Yan Cheng;Jin-Xin Song;Jie Wu;Hai-Feng Zhu(First Affiliated Hospital of Northwestern University, Xi'an Ophthalmology Hospital, Shaanxi Institute of Ophthalmology, Xi'an 710002, Shaanxi Province, China)

机构地区：[1]西北大学附属第一医院西安市眼科医院陕西省眼科研究所,中国陕西省西安市710002

出　　处：《国际眼科杂志》2020年第12期2185-2187,共3页International Eye Science

基　　金：陕西省重点研发计划(No.2020SF-273)。

摘　　要：目的:探讨不同时期眼部碱烧伤综合治疗的效果。方法:回顾分析2019-01/12我院收治的眼部碱烧伤患者124例166眼,根据病情的严重程度,采取多项综合治疗措施,分别应用药物及手术联合治疗,随访6~12mo,观察眼部碱烧伤愈合情况及疾病转归。结果:治疗后所有患者症状缓解,患眼角膜结膜愈合,无感染发生,平均住院时间13d,其中治愈118眼(71.1%),好转43眼(25.9%),无效5眼(3.0%)。眼部碱烧伤Ⅰ度、Ⅱ度患者治疗后无并发症发生;Ⅲ度患者眼表修复及视力恢复情况好于Ⅳ度患者,且并发症发生率低于Ⅳ度患者。结论:根据角膜结膜及眼睑损伤评估眼部碱烧伤程度,选择恰当的时机采取相应的治疗措施,给予全身及局部药物治疗,结合眼表冲洗、前房穿刺、羊膜移植、结膜瓣遮盖、角膜移植、角膜缘干细胞移植等综合治疗方法,可获得较好的临床疗效。AIM:To investigate the effect of comprehensive treatment of ocular alkali burn in different periods.METHOD:A retrospective analysis was performed on 124 cases(166 eyes)of ocular alkali burns admitted to our hospital from January 2019 to December 12.According to the severity of the disease,a number of comprehensive measures were taken to treat the ocular alkali burn with drugs and surgery respectively.The patients were followed up for 6-12mo to observe the healing of ocular alkali burn and the final outcome of disease.RESULTS:After treatment,the symptoms of all patients were relieved,the corneal conjunctiva healed,and no infection occurred.The average hospitalization time was 13d,totally 118 eyes were cured(71.1%),43 eyes were improved(25.9%),5 eyes were ineffective(3.0%).There was no complication in degree I and degree II of ocular alkali burn patients,degree III was better than degree IV,and the complication rate in degree III was lower than that in degree IV.CONCLUSION:According to the corneal conjunctiva and eyelid injury evaluation of ocular alkali burn degree,choose appropriate time to take corresponding treatment measures,and give systemic and local drug treatment.Combined with ocular surface irrigation,anterior chamber puncture,amniotic membrane transplantation,conjunctival flap covering,corneal transplantation,limbal stem cell transplantation and other comprehensive treatment methods can obtain good clinical effect.

关 键 词：眼碱烧伤 眼科手术 移植 羊膜 药物治疗 综合治疗 

分 类 号：R779.6[医药卫生—眼科]