磁共振功能成像在血管性痴呆诊断中的应用进展  

Application progress of functional magnetic resonance imaging in the diagnosis of vascular dementia

作　　者：王倩楠 孙慧勤[2] 宋璞[2] 赵莉[2] 张青山 WANG Qiannan;SUN Huiqin;SONG Pu;ZHAO Li;ZHANG Qingshan(Graduate School of Bengbu Medical College,Bengbu 233030,China;Xuzhou Central Hospital,Xuzhou 221009,China)

机构地区：[1]蚌埠医学院研究生院,安徽蚌埠233030 [2]徐州市中心医院,江苏徐州221009

出　　处：《中国实用神经疾病杂志》2020年第22期2015-2019,共5页Chinese Journal of Practical Nervous Diseases

基　　金：徐州市科技计划项目(编号:KC19177)。

摘　　要：血管性痴呆(vascular dementia,VaD)是在脑血管疾病基础上发生的,以记忆、认知功能缺损或伴有视空间技能和情感人格障碍的疾病。近年来发病率呈现不断上升的趋势。目前针对VaD无特效治疗,早发现、早诊断、早干预尤为重要。当前诊断VaD的主要依据是临床特点、相关量表检查及神经影像学等,缺乏特异性及敏感性高的指标。利用影像学技术,尤其是磁共振功能成像(functional magnetic resonance imaging,fMRI)诊断VaD已成为目前相关研究的热点。本文针对fMRI在VaD诊断中的应用进展进行综述。Vascular dementia(VaD)is a disease that occurs on the basis of cerebrovascular disease,and is a disease with impairment of memory and cognitive function or accompanied by visual spatial skills and emotional personality disorders.In recent years,the incidence rate has shown a rising trend.At present,there is no specific treatment for VaD,and early detection,early diagnosis,and early intervention are particularly important.The current diagnosis of VaD is mainly based on clinical characteristics,related scale examinations and neuroimaging,etc.,which lack specific and sensitive indicators.Using imaging technology,especially functional magnetic resonance imaging(fMRI)to diagnose VaD has become a hot spot in related research.This article reviews the application progress of fMRI in VaD diagnosis.

关 键 词：血管性痴呆 脑血管疾病 磁共振功能成像 磁共振波谱成像 弥散张量成像 早期诊断 

分 类 号：R743[医药卫生—神经病学与精神病学]