正常成人视网膜中心固视点与黄斑中心凹位置关系的临床研究  

A clinical study of the position relationship between the optical fixation and the fovea in healthy adults

作　　者：曹珍珎 王海林[2] 牛彤彤[2] 牛梦迪 Cao Zhenzhen;Wang Hailin;Niu Tongtong;Niu Mengdi(Postgraduate Training Base of the Fourth People's Hospital of Shenyang of Jinzhou Medical University,Shenyang 110031,China;Department of Ophthalmology,The Fourth People's Hospital of Shenyang,Shenyang 110031,China)

机构地区：[1]锦州医科大学沈阳市第四人民医院研究生培养基地,110031 [2]沈阳市第四人民医院眼科,110031

出　　处：《中华眼底病杂志》2020年第11期853-856,共4页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的观察正常成人视网膜中心固视点与黄斑中心凹的位置关系。方法回顾性临床研究。2019年8月至2020年1月于沈阳市第四人民医院进行健康体检的正常成人100名100只眼纳入研究。受试者均行BCVA、屈光度、微视野、OCT检查以及眼轴长度(AL)测量。其中,男性42名,女性58名;平均年龄(46.4±14.7)岁;平均屈光度(-1.02±1.99)D;平均AL(23.22±0.47)mm;平均黄斑中心凹无血管区(FAZ)面积(0.38±0.13)mm2。采用MP-3微视野计行中心固视检查,检查结束后设备自动拍摄高清眼底像,并自动计算视网膜中心固视点。通过Nidek Overlay功能性多模式影像平台对包含视网膜中心固视点与黄斑中心凹的图像进行叠加,观察两者位置关系,并测量两者间距离。视网膜中心固视点与黄斑中心凹中心距离和年龄、屈光度、FAZ面积行Pearson相关性分析。结果所有受试眼视网膜中心固视点均在黄斑小凹范围内,但与黄斑中心凹中心位置不重合。100只眼中,视网膜中心固视点位于鼻侧、下方、颞侧、上方分别为53、23、15、9只眼。视网膜中心固视点与黄斑中心凹中心平均距离为(158.31±71.56)μm。Pearson相关性分析发现,视网膜中心固视点与黄斑中心凹中心距离和年龄(r=0.140)、屈光度(r=-0.009)、FAZ面积(r=0.038)均无相关性(P=0.165、0.932、0.707)。结论正常成人视网膜中心固视点以中心凹鼻侧多见。Objective To observe the positional relationship between the central fixation point of the retina and the fovea in normal adults.Methods A retrospective clinical study. From August 2019 to January 2020, 100 eyes of 100 normal adults who underwent physical examination at the Fourth People's Hospital of Shenyang were included in the study. All patients underwent BCVA, diopter, microfield, OCT examination, and axial length (AL) measurement. There were 42 males and 58 females with the average age was 46.4±14.7 years. The average diopter was -1.02±1.99 D, the average AL was 23.22±0.47 mm, the average foveal avascular zone (FAZ) area was 0.38±0.13 mm2. The MP-3 microperimetry was used for central fixation examination. After the examination, high-definition fundus images were automatically taken and the central fixation point of the retina were automatically calculated by the equipment. The Nidek Overlay functional multi-mode imaging platform was used to superimpose the images containing the central fixation point of the retina and the macular fovea, the positional relationship between the two was observed, and the distance between the two was measured. Pearson correlation analysis was performed on the distance between the fixation point of the center of the retina and the center of the fovea, age, diopter, and FAZ area of the macula.Results The fixation point of the retinal center of all tested eyes was within the range of the macular fovea, which did not coincide with the center of the macular fovea. Among 100 eyes, the fixation point of the center of the retina were 53, 23, 15, and 9 eyes at the nose, lower, temporal, and upper sides, respectively. The average distance between the fixation point of the center of the retina and the center of the fovea was 158.31±71.56 μm. The distance between the fixation point of the retinal center and the center of the macular fovea and age (r=0.140), diopter (r=-0.009), FAZ area( r=0.038) were not correlated (P=0.165, 0.932, 0.707) in correlation analysis.Conclusion The centr

关 键 词：视野 黄斑/生理学 体层摄影术 光学相干 成年人 

分 类 号：R770.4[医药卫生—眼科]