CT纹理分析在胃癌中的应用研究  

CT texture analysis in gastric cancers

作　　者：范园 李宏江[1] 陈修远 贺涛 王竹[2] 陈洁[1] FAN Yuan;LI Hongjiang;CHEN Xiuyuan;HE Tao;WANG Zhu;CHEN Jie(Department of Breast Surgery,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,P.R.China;Laboratory of Molecular Diagnosis of Cancer,Cancer Center,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,P.R.China)

机构地区：[1]四川大学华西医院乳腺外科,成都610041 [2]四川大学华西医院肿瘤分子诊断实验室,成都610041

出　　处：《华西医学》2020年第11期1404-1408,共5页West China Medical Journal

基　　金：四川省科学技术厅重点研发项目(2019YFS0338)。

摘　　要：CT纹理分析(CT texture analysis,CTTA)通过提取CT图像的纹理特征,然后进行分析和定量客观的评价,可以客观地评估超出主观视觉解释能力的组织及其病变的异质性,反映组织微环境信息。该文从胃肿瘤的鉴别、胃癌分期的预测、与胃癌Lauren分型的相关性、胃癌隐匿性腹膜转移的预测、胃癌疗效及预后评估、生物标志物的预测几个方面,对近年来CTTA在胃癌中的应用进行了综述,认为CTTA在上述方面具有很好的应用前景。CT texture analysis(CTTA)can objectively evaluate the heterogeneity of tissues and their lesions beyond the ability of subjective visual interpretation by extracting the texture features of CT images,then performing analysis and quantitative and objective evaluation,reflecting the tissue micro environmental information.This article reviews the recent studies on the applications of CTTA in gastric cancers,in the aspects of identification of gastric tumors,prediction of stage,correlation with Lauren classification,prediction of occult peritoneal carcinomatosis,evaluation of efficacy and prognosis,and prediction of biomarkers.It is regarded that CTTA has a good application prospect in gastric cancers.

关 键 词：影像组学 CT纹理分析 胃癌 

分 类 号：R735.2[医药卫生—肿瘤]