Formation of Functional Cyclooctadiene Derivatives by Supramolecularly- Controlled Topochemical Reactions and Their Use as Highly Selective Fluorescent Biomolecule Probes  

作　　者：Ming-Ming Gan Ying-Feng Han 

机构地区：[1]Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education,College of Chemistry and Materials Science,Northwest University,Xi'an,Shaanxi 710127,China [2]State Key Laboratory of Structural Chemistry,Fujian Institute of Research on the Structure of Matter,Chinese Academy of Sciences,Fuzhou,Fujian 350002,Chino

出　　处：《Chinese Journal of Chemistry》2020年第10期1040-1044,共5页中国化学（英文版）

基　　金：We thank the Natural Science Foundation of Jiangsu Province(BK20181449);the Jiangsu Provincial Six Talent Peaks Project(XCL-090);the National Natural Science Foundation of China(Nos.21202141,21971065);the Priority Academic Program Devel-opment(PAPD)of Jiangsu Higher Education Institutions.

摘　　要：Summary of main observation and conclusion Controlling the regio-and stereochemistry of the photoproducts in solution is far more challenging for polvenes than for monoalkenes.Herein,a supramolecularly-controlled topochemical reaction of conjugated dienes in homogeneous system is developed,ultimately providing two cyclooctadiene-cored tetraimidazolium molecular receptors exclusively.These cyclooctadiene derivatives exhibited highly sensi-tive and selective fluorescence sensing for thymine relative to other biologically relevant species in aqueous solution at physiological pH.Both the cycloo-ctadiene moieties and imidazolium units play important roles in the selective recognition observed.The presented supramolecularly-controlled method allows the simple yet rare selective photoconversion of flexible cyclooctadiene derivatives in solution.This study offers a new synthetic strategy for the preparation of functional molecules with potential for use in biological applic ations.

关 键 词：solution. DIENE chemical 

分 类 号：O62[理学—有机化学]