从中医“气化”角度探讨自噬现象  

Discussion on autophagy from the perspective of traditional Chinese medicine’qi transformation’

作　　者：王蓓蕾[1] 阮越勇 于洋[2] 韩桂玲[2] 张纾难[1,2] WANG Bei-lei;RUAN Yue-yong;YU Yang;HAN Gui-ling;ZHANG Shu-nan(Beijing University of Chinese Medicine,Beijing 100029,China;Center for Respiratory Diseases,Department of TCM Pulmonary Diseases,China-Japan Friendship Hospital,National Clinical Research Center for Respiratory Diseases,Beijing 100029,China)

机构地区：[1]北京中医药大学,北京100029 [2]中日友好医院呼吸中心,中日友好医院中医肺病科,国家呼吸疾病临床研究中心,北京100029

出　　处：《中华中医药杂志》2020年第11期5452-5454,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81804044),国家临床重点专科。

摘　　要：自噬是真核生物细胞内普遍存在的生存机制。细胞对自身废旧物质回收再利用,完成自我更新的新陈代谢,使机体维持稳态平衡,与中医的"气化"功能相类似。自噬太过或不足均会导致机体代谢障碍而阴阳失调。自噬调节异常与气虚痰瘀密切相关。Autophagy is a ubiquitous survival mechanism in eukaryotic cells.The cells recycle and reuse their own waste materials,complete the self-renewing metabolism,and maintain the homeostasis of the body,similar to the‘qi transformation’function of Chinese medicine.Excess or deficiency of autophagy can lead to metabolic disorders and yin and yang disorders.Abnormal autophagy regulation is closely related to qi deficiency and stasis-phlegm syndrome.

关 键 词：自噬 气化 气虚痰瘀 中医 

分 类 号：R228[医药卫生—中医基础理论]