孕早期脉诊信息特征分析  

Study on the characteristics of pulse information in early pregnancy

作　　者：汪南玥[1] 吴文湘[2] 刘佳[1] 周灵运[1] 张佳琪 黄大威[1] 叶佐昌[4] WANG Nan-yue;WU Wen-xiang;LIU Jia;ZHOU Ling-yun;ZHANG Jia-qi;HUANG Da-wei;YE Zuo-chang(Experimental Research Center,China Academy of Chinese Medical Sciences,Beijing 100700,China;Peking University First Hospital,Beijing 100034,China;Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China;Tsinghua University,Beijing 100085,China)

机构地区：[1]中国中医科学院医学实验中心,北京100700 [2]北京大学第一医院,北京100034 [3]中国中医科学院西苑医院,北京100091 [4]清华大学,北京100085

出　　处：《中华中医药杂志》2020年第11期5525-5528,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：科技部基础性工作专项项目(No.2013FY114400);北京市科技新星计划项目(No.Z161100004916125);北京市科技新星计划交叉学科项目(No.Z171100001117140);中央级公益性科研院所基本科研业务费专项资金项目(No.ZZ2018011)。

摘　　要：目的:分析孕早期妇女的脉诊信息特征。方法:采集孕早期妇女的脉诊信息并与正常育龄期妇女对照进行分析。在对脉诊信息预处理后选取连续的多个周期的脉搏波作为研究对象,对各个周期进行12次谐波的最小二乘回归并建立数学模型,获取193个特征参数,根据上述参数对孕早期妇女的脉诊信息进行特征分析和分类判决,获得孕早期妇女脉诊信息的变化特征。结果:孕早期妇女的脉诊信息与正常育龄期妇女比较差异显著,判决准确率在70%~85%之间。孕早期脉诊信息变化的关键参数集中在左寸t1、左关w和右尺h1。结论:孕早期妇女的生理变化可以在桡动脉脉诊信息中得到体现,形成桡动脉脉诊信息改变的关键特征所在寸、关、尺部位与古代文献描述基本相符。Objective:To study the features in the pulse waves of women during early pregnancy.Methods:To collect the pulse waves of women during early pregnancy and compare them with normal women’s.We choosed continuous cycles waves with different period length and then do the LSQ regression by 12 harmonics fitting which were correspond with every cycle lengths to build mathematical model and extract 193 parameters after pretreatment,then did classification and identification to find the features of pregnant women’s pulse waves.Results:There were significant difference between pregnant women’s pulse waves and the normal women’s and the accurate was 70%~85%to identify,and the features distribute at different places in radial artery called zuocun t1,zuoguan w,and youchi h1 in pulse-diagnosis of TCM.Conclusion:Physiological changes of early pregnant women can embody in pulse waves we collected from the radial artery.The location of the key feature of radial artery pulse information change in cun,guan and chi consistent with the description of ancient literature.

关 键 词：孕早期 脉诊信息 特征提取 分类判决 

分 类 号：R241.1[医药卫生—中医诊断学] R271.41[医药卫生—中医临床基础]