浅谈“五脏致衰”及从神经心理学角度研究“肝失疏泄致衰”的可行性  

Discussion on’aging caused by five zang viscera’and the feasibility of studying’aging caused by liver controlling conveyance and dispersion’from the perspective of neuropsychology

作　　者：秦中朋 詹向红[1] QIN Zhong-peng;ZHAN Xiang-hong(Cognitive Neuroscience Laboratory of Henan University of Chinese Medicine,Zhengzhou 450046,China)

机构地区：[1]河南中医药大学认知神经科学实验室,郑州450046

出　　处：《中华中医药杂志》2020年第11期5665-5668,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金面上项目(No.81873208,No.81473556,No.81173148);2018年度河南省重点研发与推广专项(No.182102310269)。

摘　　要：轻度认知功能障碍(MCI)介于正常脑老化与老年痴呆的过渡性阶段,是预防和延缓进展为痴呆的关键期。缓衰益智是中医学的优势领域,中医藏象学说认为,MCI与心、肾、脾等脏腑功能失调关系密切,与肝失疏泄密不可分。文章总结了历代中医学者从五脏角度对于MCI的认识,并在课题组"长期负性情绪积累肝失疏泄致衰"科学假说基础上,提出联合使用事件相关电位和眼动技术探索"肝失疏泄致衰"的神经心理学研究思路,以期为MCI的病因病机学说增添新内涵,为中医临床肝主疏泄理论提供参考。MCI is the transitional stage between normal brain aging and dementia,and it is the key period to prevent and delay the progression to dementia.Delaying senility and improving intelligence are the advantages of traditional Chinese medicine(TCM).According to the theory of visceral manifestation,MCI is closely related to the dysfunction of heart,kidney,spleen and other viscera,and is closely related to the‘liver controlling conveyance and dispersion’.This study summarizes the understanding of MCI from the perspective of five zang viscera of TCM scholars in the past dynasties,and based on the scientific hypothesis of‘long-term negative emotion accumulation liver controlling conveyance and dispersion causing aging’,puts forward the idea of combining event-related potential and eye tracking technology to explore the neuropsychology research of‘liver controlling conveyance and dispersion can cause the aging’,in order to add new connotation to the etiology and pathogenesis theory of mild cognitive dysfunction,and provide reference for the theory of clinical‘liver controlling dispersion’of TCM.

关 键 词：轻度认知功能障碍 痴呆 肝失疏泄 五脏 事件相关电位技术 眼动技术 

分 类 号：R277.7[医药卫生—中医学]