局部进展期胃癌围手术期化疗的研究进展  

Progress of perioperative chemotherapy of locally advanced gastric cancer

作　　者：丁学伟 梁寒 Ding Xuewei;Liang Han(Department of Gastroenterological Surgery,Tianjin Medical University Cancer Hospital and Institute,Key Laboratory of Cancer Prevention and Therapy of Tianjin City,National Clinical Research Center for Cancer,Tianjin 300060,China)

机构地区：[1]天津医科大学肿瘤医院胃部肿瘤科,国家肿瘤临床医学研究中心,天津市肿瘤防治重点实验室,天津市恶性肿瘤临床医学研究中心,300060

出　　处：《国际外科学杂志》2020年第11期730-735,共6页International Journal of Surgery

摘　　要：胃癌D2根治术已成为标准治疗,基于ACTS-GC试验和CLASSIC试验的结果,胃癌D2根治术+辅助化疗成为当前标准治疗策略。新辅助化疗可以提高R0切除率,但有关新辅助化疗的方案选择、最佳疗程等方面并未达成共识。本文将回顾近年来胃癌新辅助化疗的研究进展。Gastrectomy with D2 lymph node dissection has become the global standard procedure for locally advanced gastric cancer.Based on the evidence of the clinic trials,postadjuvant chemotherapy after D2 gastrectomy is the current standard strategy.Neoadjuvant chemotherapy can increase the R0 resection rate,but the consensus has not been reached.These trials could lead to new evidence for improved treatment of gastric cancer in the near future.This review will summarize recent evidence on the benefits of for locally advanced gastric cancer.

关 键 词：胃肿瘤 药物疗法 联合 临床方案 局部进展期 新辅助治疗 

分 类 号：R735.2[医药卫生—肿瘤]