肝病患者肌肉减少症骨骼肌测量及诊治研究进展  

Progress of skeletal muscle mass evaluation,diagnosis and treatment of sarcopenia in patients with liver disease

作　　者：侯建存[1] 张雅敏[1] Hou Jiancun;Zhang Yamin(Department of Hepatobiliary Surgery,Tianjin First Central Hospital,Tianjin 300192,China)

机构地区：[1]天津市第一中心医院肝胆外科,300192

出　　处：《中华肝胆外科杂志》2020年第11期873-877,共5页Chinese Journal of Hepatobiliary Surgery

基　　金：天津市科技计划项目(19ZXDBSY00010)。

摘　　要：肝病相关的肌肉减少症是继发性肌肉减少症,亦是肝硬化患者中常见的肌肉异常,常被医生所忽视。慢性肝病患者存在食欲减低、蛋白质摄入不足、门静脉高压症造成的消化不良以及高代谢状态等使得骨骼肌消耗加速。目前肌肉减少症被公认为是肝脏外科术后发生并发症以及死亡密切相关的危险因素,影响了肝病患者的生活质量。本文对目前肌肉减少症的诊断、对肝病患者的影响和干预措施进行综述,为改善患者预后提供临床参考。Liver disease-associated sarcopenia is a type of secondary sarcopenia,which is a common muscle abnormality in patients with liver cirrhosis and is often ignored by doctors.Patients with chronic liver disease often have reduced appetite,insufficient protein intake,indigestion caused by portal hypertension,and high metabolism,which accelerate the wasting of skeletal muscle.At present,sarcopenia is recognized as a risk factor which is closely related with postoperative complications and morbidity in liver surgery,and also affects the quality of life of patients with liver disease.This article reviews the current diagnosis and treatment options of sarcopenia and the impact of sarcopenia on the prognosis of liver disease,thus to provide references in clinical practice.

关 键 词：肝切除术 肝移植 预后 肌肉减少症 骨骼肌指数 

分 类 号：R575[医药卫生—消化系统] R685[医药卫生—内科学]