胃促生长素在胆系炎症及胃肠动力障碍中的作用  

Role of ghrelin in biliary inflammation and related gastrointestinal dysmotility

作　　者：宣佳磊 吴高珏 龚镭 Xuan Jialei;Wu Gaojue;Gong Lei(Department of Gastroenterology,the Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University,Wuxi 214002,China)

机构地区：[1]南京医科大学附属无锡第二医院消化内科,无锡214002

出　　处：《中华肝胆外科杂志》2020年第11期877-880,共4页Chinese Journal of Hepatobiliary Surgery

基　　金：无锡市科教强卫工程医学重点学科(胃肠病学)项目(ZDXK002);无锡市科教强卫工程青年医学重点人才项目(QNRC066)。

摘　　要：胆系感染是消化系统常见疾病,可引起脓毒症等严重并发症,尤其是重症感染患者往往预后不良。胃促生长素在炎症控制、胃肠运动、食欲调节、内分泌活动等方面均有作用,且在胆系感染的炎症反应及其导致的胃肠动力障碍中的作用已成为近年的研究热点。本文就其相关作用做一综述。Biliary infection is a common disease in the digestive system,can cause serious complications including sepsis.Among them,patients with severe biliary infections often have poor prognosis.It is reported that ghrelin play important roles in regulating inflammatory response,gastrointestinal motility,appetite,and endocrine.Recently the therapeutic role of ghrelin in the biliary infection has been studied.This article reviews the effects of ghrelin on inflammatory reaction and gastrointestinal dysmotility in biliary infections.

关 键 词：胃促生长素 炎症 胆系感染 胃肠动力 

分 类 号：R575[医药卫生—消化系统]