泮托拉唑治疗消化道溃疡出血患者的止血效果分析  

Analysis of hemostatic effect of pantoprazole in the treatment of patients with peptic ulcer bleeding

作　　者：任芳芳 Ren Fangfang(Department of Gastroenterology,Chaoyang Central Hospital,Chaoyang,Liaoning,122000,China)

机构地区：[1]朝阳市中心医院消化内科,辽宁朝阳122000

出　　处：《当代医学》2020年第35期85-87,共3页Contemporary Medicine

摘　　要：目的探讨泮托拉唑治疗消化道溃疡出血患者的止血效果。方法选择2017年6月至2019年8月在本院就诊的消化道溃疡患者126例作为研究对象,采用随机数表法分为两组,各63例。所有患者入院后,均给予常规基础治疗,对照组患者在此基础上予以奥美拉唑治疗,观察组采用泮托拉唑进行治疗,比较两组临床疗效、平均止血时间、平均呕血次数、黑便次数以及治疗后第1、3、5天出血情况。结果治疗后,两组疗效比较差异无统计学意义;治疗第1、3、5天后,观察组出血量少于对照组,差异有统计学意义(P<0.05);治疗后,观察组平均止血时间、住院时间均短于对照组,平均呕血次数、黑便次数均少于对照组,差异有统计学意义(P<0.05)。结论消化道溃疡出血患者使用泮托拉唑具有理想效果,止血迅速,能明显改善患者出血症状,缩短止血以及住院时间,值得临床推广应用。Objective To investigate the hemostatic effect of pantoprazole in the treatment of patients with peptic ulcer bleeding.Methods 126 peptic ulcer patients who were treated in our hospital from June 2017 to August 2019 were selected as the research objects,and were divided into two groups by random number table method,with 63 cases in each group.After admission,all patients were given conventional basic treatment.On this basis,patients in the control group were treated with omeprazole,and the observation group was treated with pantoprazole.The clinical efficacy,average hemostasis time,average number of hematemesis,and and melena were compared between the two groups on days 1,3,and 5 after treatment.Results After treatment,there was no significant difference in curative effect between the two groups;after the first 1,3,and 5 days of treatment,the bleeding volume of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the observation group averaged hemostasis the time and hospital stay were shorter than those of the control group,and the average number of hematemesis and melena were less than those of the control group,the difference was statistically significant(P<0.05).Conclusion The use of pantoprazole in patients with gastrointestinal ulcer bleeding has an ideal effect,rapid hemostasis,can significantly improve the bleeding symptoms of patients,reduce hemostasis and hospitalization time,clinically worthy of promotion and application.

关 键 词：消化道溃疡出血 泮托拉唑 止血效果 

分 类 号：R573.1[医药卫生—消化系统]