多次睡眠潜伏期试验的检测方法及临床应用进展  

Progress in detection methods and clinical application of multiple sleep latency test

作　　者：陈坤 徐云霞 程文彬 吴敏录 赵忠新 吴惠涓 Chen Kun;Xu Yunxia;Cheng Wenbin;Wu Minlu;Zhao Zhongxin;Wu Huijuan(Department of Neurology,Changzheng Hospital Affiliated to Naval Medical University,Shanghai 200003,China)

机构地区：[1]海军军医大学附属长征医院神经内科,上海200003

出　　处：《神经疾病与精神卫生》2020年第8期591-595,共5页Journal of Neuroscience and Mental Health

基　　金：上海市科技委员会科研计划项目(19ZR1457000)。

摘　　要：应用多导睡眠仪(PSG)进行多次睡眠潜伏期试验(MSLT)是客观评价日间思睡严重程度的标准工具。分析多次试验的睡眠次数、平均睡眠潜伏期以及快速眼动(REM)睡眠出现的潜伏期与次数,能将思睡的严重程度用睡眠潜伏期的长短显示出来,更具有客观性和可重复性。目前MSLT在临床已广泛用于发作性睡病的诊断,特发性睡眠增多和阻塞性睡眠呼吸暂停综合征等日间思睡的严重程度评估,以及精神振奋剂等药物的疗效评估。现对MSLT的具体检测方法及临床应用作一综述。Multiple sleep latency test(MSLT)is an objective evaluation and a standard tool of the daytime sleepiness.Polysomnography(PSG)was used to conduct multiple sleep latency test.The sleep frequency,average sleep latency,and the latency and frequency of rapid eye movement(REM)sleep were analyzed.The severity of sleepiness could be displayed by MSLT with the length of the sleep latency,which is more objective and repeatable.Now MSLT has been widely used in clinical diagnosis of narcolepsy,the severity evaluation of daytime sleepiness and obstructive sleep apnea-hypopnea syndrome,and the efficacy evaluation of drugs such as psychostimulants.

关 键 词：睡眠障碍 多次睡眠潜伏期试验 综述 

分 类 号：R740[医药卫生—神经病学与精神病学]