急性应激和性别对健康被试感觉门控的影响  

Acute stress and gender effects in sensory gating in normal subjects

作　　者：辛增友 陈安梅[3] 李红 XIN Zengyou;CHEN Anmei;LI Hong(Brain and Cognitive Neuroscience Research Center,Liaoning Normal University,Dalian,Liaoning 116029,China;School of Education Science,Minnan Normal University,Zhangzhou,Fujian 363000,China;Zhangzhou Institute of Technology,Zhangzhou,Fujian 363000,China;College of Psychology and Sociology,Shenzhen University,Shenzhen,Guangdong 518060,China)

机构地区：[1]辽宁师范大学脑与认知神经科学研究中心,辽宁大连116029 [2]闽南师范大学教育科学学院,福建漳州363000 [3]漳州职业技术学院,福建漳州363000 [4]深圳大学心理与社会学院,广东深圳518060

出　　处：《闽南师范大学学报（自然科学版）》2020年第4期117-125,共9页Journal of Minnan Normal University：Natural Science

基　　金：福建省中青年教师教育科研项目(JA15320)。

摘　　要：感觉门控是病理学研究的热点,然而健康个体中其影响因素研究却很有限.本研究的目标是澄清急性应激和性别在感觉门控中的效应.研究表明,应激干预减弱了对S2诱发的P50成分抑制,而对S1诱发的P50反应没影响,导致P50门控显著更差;急性应激还损害了注意分配;女性有更好的N100和P200门控,且在S1和S2诱发的N100振幅和S1诱发的P200振幅上,女性有显著更高的反应.Sensory gating is one of the foci of psychopathological researches.However sensory gatings of healthy subjects seemed to be affected by several factors.The objective was to clarify the effects of acute stress and gender in sensory gatings.Data showed acute stress impaired inhibition of P50 to S2 without effects on sensory registration leading to worse P50 sensory gating,and disrupted attentional allocation reflected by attenuated P200 responses than control treatment,without difference between genders.As for N100 and P200 gatings,women showed slightly better than men without effects of acute stress.Data also showed slightly larger N100 amplitudes across clicks and a significant larger P200 amplitude to S1 for women.

关 键 词：急性应激 感觉门控 P50 N100 P200 

分 类 号：B842.2[哲学宗教—基础心理学]