血清LP-PLA2、CyPA与急性脑梗死后抑郁的相关性研究  

Relationship between Serum LP-PLA2, CyPA and Depression after Acute Cerebral Infarction

作　　者：刘唱 和梅[2] Liu Chang;He Mei(Jiamusi University,Jiamusi 154000;The First Affiliated Hospital of Jiamusi University,Jiamusi 154000,China)

机构地区：[1]佳木斯大学,黑龙江佳木斯154000 [2]佳木斯大学附属第一医院,黑龙江佳木斯154000

出　　处：《广东化工》2020年第21期76-77,共2页Guangdong Chemical Industry

摘　　要：脑卒中是一种急性脑血管病,包括缺血性卒中和出血性卒中。目前卒中相关死亡人数在逐年增加,而脑梗死在其中更为常见。梗死后抑郁(post-stroke depression,PSD)是主要的并发症之一,严重影响患者卒中后神经功能的恢复及回归社会的能力,增加致残率、死亡率和卒中复发率,尽管预防和治疗取得了进展,但其仍然是影响患者和家庭生活的严重疾病问题,有研究表明,炎性反应在脑梗死后抑郁症病理过程中发挥着重要作用。本文对脂蛋白相关磷脂酶A2、亲环素A与急性脑梗死后抑郁相关性的研究进展进行阐述。Stroke is an acute cerebrovascular disease, which includes ischemic stroke and hemorrhagic stroke. The number of stroke-related deaths is increasing year by year, and cerebral infarction is more common. Post-stroke depression is one of the major complications, which seriously affects the recovery of neural function and the ability to return to society after stroke, and increases the rate of disability, mortality and recurrence of stroke despite progress in prevention and treatment, however, it is still a serious disease problem that affects patients and family life. Some studies show that inflammatory reaction plays an important role in the pathological process of post-infarction depression. This article reviews the research progress of the relationship between lipoprotein-associated phospholipase A2, Cyclophilin A and post-infarction depression.

关 键 词：脂蛋白相关磷脂酶A2 亲环素A 急性脑梗死后抑郁 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R446.1[医药卫生—临床医学]