非小细胞肺癌影像基因组学  

Radiogenomics in non-small cell lung cancer

作　　者：杨蕾[1] 张传玉[1] 张在先 刘欢[1] Yang Lei;Zhang Chuanyu;Zhang Zaixian;Liu Huan(Department of Radiology,Affiliated Hospital of Qingdao University,Qingdao 266000,China)

机构地区：[1]青岛大学附属医院放射科,266000

出　　处：《国际肿瘤学杂志》2020年第9期555-559,共5页Journal of International Oncology

摘　　要：影像基因组学用影像组学方法探索影像学特征与基因表达模式之间的联系,具有无创、能显示肿瘤整体信息的特点。影像组学的应用对预测非小细胞肺癌(NSCLC)的基因突变具有一定作用,是近年来研究的热点。影像组学特征与常规影像学特征、临床特征等联系起来,可提供肿瘤的多方位信息,在NSCLC驱动基因表型的预测和精准治疗中将发挥越来越重要的作用。Radiogenomics explores the relationship between imaging features and gene expression patterns using radiomics,which is non-invasive and can present the overall information of tumors.The application of radiomics,somewhat effective in predicting gene mutations in non-small cell lung cancer(NSCLC),has recently become a research focus.Radiomic features,combined with conventional imaging,clinical and other features,can provide multi-directional information on tumors and play an increasingly important role in the prediction and precise treatment of NSCLC-driving gene phenotypes.

关 键 词：癌 非小细胞肺 受体 表皮生长因子 间变性淋巴瘤激酶 KRAS基因 影像组学 

分 类 号：R734.2[医药卫生—肿瘤]