阑尾孔周围点片状炎性病变提升溃疡性结肠炎诊断效率  

Improving the Diagnostic Accuracy of Ulcerative Colitis by Inflammation in Peri-Appendiceal Orifice

作　　者：邓澎[1] 张淼[1] 潘攀 吴俊超[2] Deng Peng;Zhang Miao;Pan Pan(Department of Emergency Medicine,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,China)

机构地区：[1]四川大学华西医院急诊科,四川成都610041 [2]四川大学灾难医学中心,四川成都610041

出　　处：《四川医学》2020年第11期1109-1112,共4页Sichuan Medical Journal

基　　金：四川省科技厅重点研发项目(编号:2018ZDYF1831)。

摘　　要：目的探讨内镜下阑尾孔周围点片状炎性病变伴远端弥漫性结直肠炎对溃疡性结肠炎的诊断意义。方法前瞻性队列研究收集了四川大学华西医院2018年1月至2019年12月所有符合条件的远端结直肠弥漫性炎性病变患者,内镜下有阑尾孔周围点片状炎性改变的患者为观察组,无阑尾孔周围点片状炎性改变的患者为对照组。结合两组患者的病史、内镜检查结果、病理结果及半年后肠镜复查结果,分析阑尾孔周围点片状炎性病变对溃疡性结肠炎诊断的意义。结果共纳入120例内镜下远端结直肠弥漫性炎性病变患者,其中观察组29例患者,28例(96.5%)确诊溃疡性结肠炎;对照组91例患者,71例(78.0%)确诊溃疡性结肠炎。阑尾孔周围点片状炎性病变对于溃疡性结肠炎的诊断特异性95.2%,敏感性为28.3%,观察组对溃疡性结肠炎的诊断率准确率明显高于对照组(96.5%vs 78.0%,P<0.05)。结论本研究发现内镜下阑尾孔周围点片状炎性病变伴远端结直肠弥漫性炎性病变提高了溃疡性结肠炎的诊断效率。Objective To explore the diagnostic value of inflammation in peri-appendiceal orifice complicated with distal diffuse colitis and proctitis for ulcerative colitis.Methods All patients with diffuse inflammation in distal colorectal from January 2018 to December 2019 were recruited in a prospective cohort study in West China hospitasl of sichuan university.The patients with inflammation in peri-appendiceal orifice were enrolled in observation group and those without it were recruited in control group.The resulits of clinical manifestation,endoscopy pathological and reexamination of endoscopy were analyzed to explore the diagnostic value of the inflammation in peri-appendiceal orifice for ulcerative colitis.Results A total of 120 patients with diffuse inflammation in the distal colorectal were collected.28 patients(96.5%)were diagnosed with ulcerative colitis in observation group(n=29)and 71 patients(78.0%)were diagnosed with ulcerative colitis in control group(n=91).The diagnostic specificity of inflammation in peri-appendiceal orifice for ulcerative colitis was 95.2%and the sensitivity was 28.3%.The diagnostic rate of ulcerative colitis was higher in observation group than that in control group(96.5%vs.78.0%,P<0.05).Conclusion Inflammation in peri-appendiceal orifice complicated with diffuse inflammation in the distal colorectal has improved the diagnostic efficiency of ulcerative colitis.

关 键 词：溃疡性结肠炎 阑尾孔 跳跃性病变 

分 类 号：R574.62[医药卫生—消化系统]