容积旋转调强结合肝动脉化疗栓塞术治疗原发性肝癌的疗效及对肿瘤标志物的影响  

Efficacy of Volumetric Modulated Arc Therapy Combined with Transcatheter Arterial Chemoembolization for the Treatment of Primary Liver Cancer and the Impact on Tumor Markers

作　　者：杨欣[1] 李玉胜 方亚玲 孙欣[1] YANG Xin;LI Yusheng;FANG Yaling;SUN Xin(Department of Radiotherapy,the First Affiliated Hospital of Anhui Medical University,Hefei 230022,China)

机构地区：[1]安徽医科大学第一附属医院放疗科,安徽合肥230022

出　　处：《临床医学工程》2020年第12期1633-1634,共2页Clinical Medicine & Engineering

摘　　要：目的探讨容积旋转调强(VMAT)结合肝动脉化疗栓塞术(TACE)治疗原发性肝癌的临床疗效。方法88例原发性肝癌患者随机均分为两组,对照组采用TACE治疗,观察组采用VMAT结合TACE治疗,比较两组的疗效和肿瘤标志物水平。结果观察组的稳定率为88.64%,显著高于对照组的70.45%(P<0.05)。治疗后,观察组的CA199、AFP、VEGF水平显著低于对照组(P<0.05)。结论VMAT结合TACE治疗原发性肝癌患者的效果显著,可有效降低血清肿瘤标志物水平。Objective To explore the clinical efficacy of volumetric modulated arc therapy(VMAT)combined with transcatheter arterial chemoembolization(TACE)for the treatment of primary liver cancer.Methods 88 patients with primary liver cancer were randomly and equally divided into two groups.The control group was treated with TACE,and the observation group was treated with VMAT combined with TACE.The efficacy and levels of tumor markers were compared between two groups.Results The stability rate of observation group was 88.64%,significantly higher than 70.45%of control group(P<0.05).After treatment,the levels of CA199,AFP and VEGF of observation group were significantly lower than those of control group(P<0.05).Conclusions VMAT combined with TACE for the treatment of patients with primary liver cancer has significant effect,and can effectively reduce the levels of serum tumor markers.

关 键 词：容积旋转调强 肝动脉化疗栓塞术 原发性肝癌 肿瘤标志物 

分 类 号：R735.7[医药卫生—肿瘤]