色素内镜在早期大肠癌诊断中的应用价值  

Value of pigment endoscopy in diagnosis of early colorectal cancer

作　　者：李霞 Li Xia(Department of Gastroenterology,Linfen Central Hospital,Linfen 041000,China)

机构地区：[1]山西省临汾市中心医院消化科,041000

出　　处：《中国实用医刊》2020年第22期75-77,共3页Chinese Journal of Practical Medicine

摘　　要：目的:分析色素内镜在早期大肠癌诊断中的应用价值。方法:抽取2017年10月至2020年2月临汾市中心医院收治的大肠黏膜病变患者65例,依据随机双盲原则分为两组。对照组32例予以常规内镜检查(不进行染色)及单纯病理活检;观察组33例采用0.4%靛胭脂和0.2%醋酸黏膜染色剂染色后进行内镜检查,对染色区域进行病理活检。比较两组病理活检率及内镜诊断结果,并将病理诊断结果作为标准,统计观察组染色前后大肠癌的诊断符合率。结果:观察组病理活检率为54.55%(18/33),低于对照组的100%(32/32),差异有统计学意义(P<0.05)。观察组炎性或者增生性息肉、腺瘤以及癌或癌变的诊断率均高于对照组,差异有统计学意义(χ^2=9.85、6.24、6.78,P<0.05)。观察组患者染色前大肠癌诊断符合率3.03%(1/33),低于染色后的诊断符合率24.24%(8/33),差异有统计学意义(χ^2=6.30,P=0.01)。结论:大肠黏膜病变采用色素内镜检查有助于其病理类型的确诊,病理活检的成功率较高,能提高大肠癌患者的早期诊断率。Objective To analyze the value of pigmented endoscopy in the diagnosis of early colorectal cancer.Methods A total of 65 patients with colorectal mucosal lesions admitted to Linfen Central Hospital from October 2017 to February 2020 were selected,and they were randomly divided into the two groups according to double blind principle.Thirty-two patients in the control group were treated with conventional endoscopy(without staining),and simple pathological biopsy was used;Thirty-three patients in the observation group were stained with 0.4%indigo rouge and 0.2%acetate mucosal stain,and the areas were stained,and pathological biopsy of the stained area was performed.The pathological biopsy rate and endoscopic diagnosis results were compared between the two groups,and the pathological diagnosis results were used as the standard,and the diagnosis coincidence rate of colorectal cancer before and after staining was calculated.Results The pathological biopsy rate in the observation group was 54.55%(18/33),which was lower than 100%(32/32)in the control group,and the difference between the groups was significant(P<0.05).The diagnostic rates of hyperplastic polyps,adenomas,cancer or cancer in the observation group were significantly higher than those in the control group,and there were significant differences between the groups(χ2=9.85,6.24,6.78,P<0.05).The diagnosis coincidence rate of colorectal cancer before staining in the observation group was 3.03%(1/33),which was lower than the diagnosis coincidence rate after staining 24.24%(8/33),and the difference was statistically significant(χ2=6.30,P=0.01).Conclusions Colorectal endoscopy is helpful for the diagnosis of colorectal mucosal lesions,and the success rate of pathological biopsy is higher,and it can improve the early diagnosis of colorectal cancer patients.

关 键 词：大肠癌 色素内镜 病理活检 

分 类 号：R742.1[医药卫生—神经病学与精神病学]