Multiple schwannomas with pseudoglandular element synchronously occurring under the tongue:A case report  

作　　者：Yong-Lin Chen Deng-Qi He Hai-Xia Yang Yu Dou 

机构地区：[1]Department of Pathology,The First Hospital of Lanzhou University,Lanzhou 730000,Gansu Province,China [2]Department of Oral Surgery,The First Hospital of Lanzhou University,Lanzhou 730000,Gansu Province,China [3]Department of Pathology,Gansu General Hospital of Armed Police,Lanzhou 730030,Gansu Province,China [4]Department of Radiology,The First Hospital of Lanzhou University,Lanzhou 730000,Gansu Province,China

出　　处：《World Journal of Clinical Cases》2020年第22期5611-5617,共7页世界临床病例杂志

基　　金：Supported by Basic Clinical Fund Project of The Fist Hospital of Lanzhou University,No.ldyyyn2015-04.

摘　　要：BACKGROUND Schwannoma is a rare benign,encapsulated tumor of the nerve sheath under the tongue,mostly occurring as solitary tumors with classical histological pattern and several common morphological variants.To our knowledge,multiple schwannomas with pseudoglandular element synchronously occurring under the tongue are rare;we report herein the first such case.CASE SUMMARY A 53-year-old man had first noticed an isolated asymptomatic mass under the tongue,and as the mass grew,the tongue was elevated.Physical examination showed multiple oval neoplasms,and the overlying mucosa was normal.Computed tomography showed three low-density oval neoplasms under the tongue,which were cystic-solid with unclear boundary.The patient has no cutaneous tumors,VIII nerve tumors,or lens opacities and no history of neurofibromatosis 2 or confirmed schwannomatosis in any first-degree relative.Magnetic resonance imaging showed no evidence of vestibular schwannoma.The preoperative diagnosis was mucoepidermoid carcinoma.During hospitalization,all neoplasms were completely excised by surgeons through an intraoral approach under general anesthesia.The diagnosis of the multiple schwannomas with pseudoglandular element was made by histopathology after surgery.At the 15-mo follow-up visit,the patient had no sign of recurrence or development of other peripheral nerve tumors.CONCLUSION Although rare,multiple schwannomas with pseudoglandular element do exist in patients presenting with masses under the tongue.Oral surgeons should be aware of the existence of multiple schwannomas with pseudoglandular element when considering masses under the tongue due to the different prognosis between multiple schwannomas with pseudoglandular element and mucoepidermoid carcinoma.

关 键 词：Case report Multiple schwannomas Pseudoglandular variant TONGUE Mucoepidermoid carcinoma 

分 类 号：R739.86[医药卫生—肿瘤]