靛红双腙类化合物生物活性的研究进展  

Research Progress in Bioactivity of Isatin Dihydrazone Compounds

作　　者：余婕 于健[1] 严国兵[1] YU Jie;YU Jian;YAN Guo-bing(Lishui University,Lishui Zhejiang 323000,China)

机构地区：[1]丽水学院,浙江丽水323000

出　　处：《辽宁化工》2020年第11期1398-1404,共7页Liaoning Chemical Industry

基　　金：丽水市科技局高层次人才培养资助项目(项目编号:2017RC12)。

摘　　要：靛红双腙类化合物是一种重要的靛红衍生物,具有多种生物活性。为了进一步研究靛红双腙类化合物的生物活性与其构效关系,近年来人们对其结构进行了大量的修饰和改造,合成了一些活性较强的化合物。对近年来靛红双腙类化合物的生物活性及构效关系研究进行了综述。Isatin dihydrazone compounds are important derivative of isatin,which has many biological activities.For further researching the relationship between the bioactivity and the structure-activity of isatin dihydrazone compounds,numerous modifications of isatin dihydrazone compounds have been carried out in recent years,and some compounds with strong activity have been synthesized.In this paper,research progress in biological activities and structure-activity relationships of isatin dihydrazone compounds was reviewed.

关 键 词：靛红衍生物 靛红双腙 生物活性 

分 类 号：R914.5[医药卫生—药物化学]