影响肝癌介入治疗患者并发栓塞性胆囊炎的危险因素Logistic回归分析  

Logistic regression analysis of risk factors affecting embolization cholecystitis in patients with interventional therapy for liver cancer

作　　者：胡添松 彭新建[1] 陈宗杰 张文华[2] HU Tiansong;PENG Xinjian;CHEN Zongjie;ZHANG Wenhua(Department of Interventional Medicine,the 909th Hospital of Joint Logistics Support Force of PLA,Zhangzhou 363000,China;Department of General Surgery,the 909th Hospital of Joint Logistics Support Force of PLA,Zhangzhou 363000,China)

机构地区：[1]中国人民解放军联勤保障部队909医院介入科,福建漳州363000 [2]中国人民解放军联勤保障部队909医院普外科,福建漳州363000

出　　处：《胃肠病学和肝病学杂志》2020年第12期1354-1358,共5页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的采用Logistic回归分析法分析影响肝癌介入治疗患者并发栓塞性胆囊炎的危险因素。方法回顾性分析2014年8月至2019年8月我院收治的62例肝癌介入治疗患者术后并发栓塞性胆囊炎的临床资料,记为A组;另根据配对原则回顾性分析同时间段我院收治的73例肝癌介入治疗患者术后未并发栓塞性胆囊炎的临床资料,记为B组。分析肝癌介入治疗患者并发栓塞性胆囊炎的相关因素。结果A组所有患者栓塞性胆囊炎经对症治疗均恢复;两组年龄、性别、远端转移、肝功能分级、肿瘤类型、肿瘤位置、合并糖尿病、合并肝血管瘤、合并肝硬化患者构成比比较,差异均无统计学意义(P>0.05);A组肿瘤直径≥10 cm、肝脏手术史、术前胆道阻塞、碘化油用量≥15 ml、胆囊动脉解剖变异患者构成比与B组比较均较高,差异有统计学意义(P<0.05),且经Logistic回归分析发现均是导致肝癌介入治疗患者并发栓塞性胆囊炎的独立危险因素(OR=3.717、2.790、2.581、2.347、2.535,P<0.05)。结论导致肝癌介入治疗患者并发栓塞性胆囊炎发生的危险因素较多,临床中应给予充分重视并制定有效应对措施,降低栓塞性胆囊炎发生率。Objective To analyze the risk factors of embolization cholecystitis in patients with interventional therapy for liver cancer by Logistic regression analysis.Methods The clinical data of 62 patients with embolic cholecystitis after interventional therapy for liver cancer admitted to our hospital from Aug.2014 to Aug.2019 were retrospectively analyzed.They were recorded as group A.In addition,according to the principle of pairing,the clinical data of 73 patients with liver cancer who underwent interventional therapy without complication of embolic cholecystitis were retrospectively analyzed and recorded as group B.The related factors of embolic cholecystitis in patients with liver cancer undergoing interventional therapy were analyzed.Results All patients in group A recovered from embolic cholecystitis after symptomatic treatment.There were no significant differences in the age,gender,distal metastasis,liver function classification,tumor type,tumor location,diabetes mellitus,hepatic hemangioma,and cirrhosis patients between the two groups(P>0.05).The proportion of patients with concurrent tumors more than or equal to 10 cm in diameter,history of liver surgery,preoperative biliary obstruction,iodized oil consumption more than or equal to 15 ml and anatomical variation of gallbladder artery in the group A were higher than those in the group B(P<0.05),which were the independent risk factors for embolization of cholecystitis in patients with liver cancer by Logistic regression analysis(OR=3.717,2.790,2.581,2.347,2.535,P<0.05).Conclusion There are many risk factors for the development of embolization cholecystitis in patients with interventional therapy for liver cancer.The clinical attention should be given and effective measures should be taken to reduce the incidence of embolic cholecystitis.

关 键 词：肝癌 介入治疗术 栓塞性胆囊炎 危险因素 

分 类 号：R735.7[医药卫生—肿瘤]