FibroTouch对自身免疫性肝病肝纤维化的诊断效能及其影响因素  

FibroTouch diagnostic efficiency and influencing factors for liver fibrosis in autoimmune liver diseases

作　　者：闫静静 王玮珺 范慧倩 潘晓莉[1] 杜凡[1] 邓晓玲[1] 宋宇虎[1] 叶进[1] 徐可树[1] 杨玲[1] Yan Jinging;Wang Weijiun;Fan Hluiqian;Pan Xiaoli;Du Fan;Deng Xiaoling;Song Yuhu;Ye Jin;Xu Keshu;Yang Ling(Department of Gastroenterology,Union Hospital,Tongi Medical College,Huazhong University of Science and Technology,Wuthan 430000,China)

机构地区：[1]华中科技大学同济医学院附属协和医院消化内科,武汉430000

出　　处：《中华肝脏病杂志》2020年第12期1048-1051,共4页Chinese Journal of Hepatology

基　　金：国家自然科学基金(81974078、81570530、81370550)。

摘　　要：FibroTouch(FT)已被广泛投入临床使用,在研究FT对自身免疫性肝病(AILD)肝纤维化的诊断效能及分析影响肝脏硬度值(LSM)的因素中发现,FT对AILD肝纤维化具有良好的诊效效能,尤其对AIH肝纤维化具有良好的诊断准确性,但用于原发性胆汁性胆管炎及其与自身免疫性肝炎重叠综合征患者时,需谨慎对待结果。与血清学模型比较,FT的诊断效能与Forns指数相当。FT用于诊断AILD时,其弹性硬度值受年龄、总胆汁酸.凝血酶原时间标准化比值、纤维蛋白原指数、凝血酶原时间5个因素影响。FibroTouch(FT)has been used widely in clinic.Studies of the FT diagnostic efficiency and influencing factors of liver stiffiness measurement(LSM)of liver fibrosis in autoimmune liver diseases(AILD)have shown that FT has a good diagnostic efficiency and accuracy,especially in AIH.However,for patients with primary biliary cholangitis and overlap syndrome of autoimmune hepatitis,FT results should be vigilant.In addition,the diagnostic efficiency of FT.Notably,when using FT to diagnose AILD,the value of elastic stffness depends on five influencing factors,such as,age,total bile acid,international standardized ratio,FlB-4 indcx,and prothrombin time.

关 键 词：肝纤维化 瞬时弹性成像技术 自身免疫性肝病 肝活体组织检查 

分 类 号：R575.2[医药卫生—消化系统]