OCTA在评估高度近视眼底形态及血流变化中应用的研究进展  

Progress of Application of OCTA in Evaluating Fundus Morphology and Microvasculature Changes in High Myopia

作　　者：罗金香 肖满意[1] 段宣初[1,2,3] Jinxiang Luo;Manyi Xiao;Xuanchu Duan(Department of Ophthalmology,Second Xiangya Hospital,Central South University,Changsha 410011,China;Changsha Aier Eye Hospital,Changsha 410015,China;Aier School of Ophthalmology,Central South University,Changsha 410015,China)

机构地区：[1]中南大学湘雅二医院眼科,长沙410011 [2]长沙爱尔眼科医院,长沙410015 [3]中南大学爱尔眼科学院,长沙410015

出　　处：《中华眼视光学与视觉科学杂志》2020年第10期789-795,共7页Chinese Journal Of Optometry Ophthalmology And Visual Science

基　　金：国家自然科学基金面上项目(81670859,81970801);湖南省自然科学基金(2019JJ40001);长沙市科技局重点研发项目(kh1801229);爱尔眼科医院集团科研基金研究所立项项目(AR1906D1,AM1906D2)。

摘　　要：近视是世界范围内发病率最高的眼部疾病,且发病原因尚不明确,是全球关注的公共卫生问题。高度近视眼及其眼底并发症严重影响视功能。光学相干断层扫描血管成像(OCTA)技术是一种对视网膜、脉络膜自动精确分层,通过量化血流面积、无血流面积和血流密度区域,对视网膜、脉络膜多层面进行定性、定量的研究手段。应用OCTA,可对高度近视眼的发病机制从视网膜各层次微血管层面进行深入研究。笔者就高度近视眼底形态改变以及OCTA在评估高度近视眼底结构、功能及血流密度变化中的应用进行综述,期望为高度近视发病机制探究及干预提供指导。Myopia,a leading cause of blindness,and the pathogenesis is unclear,is considered to be a public health problem worldwide.High myopia and its fundus complications seriously impair visual function.Optical coherence tomography angiography(OCTA)is an automatic and accurate delamination of the retina and choroid,which can qualitatively and quantitatively detect the retina and choroid by quantifying the microvasculature area.OCTA can be used to detect the pathogenesis of high myopia at the microvascular level of the retina.This review summarizes the morphological changes of the fundus in high myopia and the application of OCTA in evaluating the changes in fundus structure,function and microvasculature density in high myopia.

关 键 词：高度近视 光学相干断层扫描血管成像 视网膜神经纤维层 视网膜血流密度 脉络膜血流密度 

分 类 号：R778.11[医药卫生—眼科]