全胸腔镜手术、胸腔镜辅助小切口手术和传统开胸手术对肺癌患者生存及并发症的影响  

Effect of complete video-assisted thoracoscopic surgery,video-assisted minithoracotomy and traditional thoracotomy on survival and complications in patients with lung cancer

作　　者：王总飞 杨慧远 刘先本 张瑞祥 刘士磊 WANG Zongfei;YANG Huiyuan;LIU Xianben;ZHANG Ruixiang;LIU Shilei(Department of Thoracic Surgery,Affiliated Cancer Hospital of Zhengzhou University,Zhengzhou 450008,He’nan,China;Department of Radiology,Affiliated Cancer Hospital of Zhengzhou University,Zhengzhou 450008,He’nan,China)

机构地区：[1]郑州大学附属肿瘤医院胸外科,郑州450008 [2]郑州大学附属肿瘤医院放射科,郑州4500080

出　　处：《癌症进展》2020年第23期2427-2430,共4页Oncology Progress

摘　　要：目的探讨全胸腔镜手术(cVATS)、胸腔镜辅助小切口手术(VAMT)与传统开胸手术对肺癌患者生存及术后并发症发生情况的影响。方法根据手术方式的不同将13 3例肺癌患者分为cVATS组(n=43例)、VAMT组(n=46)和传统开胸组(n=44)。比较3组患者的术中指标、术后指标、术后并发症发生情况和5年生存率。结果cVATS组、VAMT组患者的术中出血量、术后数字评价量表(NRS)评分、胸腔引流时间、术后住院时间均少于传统开胸组,且cVATS组患者的术后NRS评分、胸腔引流时间、术后住院时间均少于VAMT组(P<0.05)。cVATS组、VAMT组患者的术后并发症总发生率均低于传统开胸组(P <0.05)。3组患者的术后5年累积生存率比较,差异无统计学意义(P> 0.05)。结论 cVATS、VAMT和传统开胸手术治疗对肺癌患者术后5年累积生存率的影响无明显差别。cVATS、VAMT更能减少术中出血量,缩短胸腔引流时间和术后住院时间,减轻疼痛,减少术后并发症的发生。Objective To investigate the effect of complete video-assisted thoracoscopic surgery(cVATS),video-assisted minithoracotomy(VAMT)and traditional thoracotomy on survival rate and postoperative complications in patients with lung cancer.Method One hundred and thirty-three patients with lung cancer were divided into cVATS group(n=43),VAMT group(n=46)and traditional thoracotomy group(n=44)according to different surgical procedures.Intraoperative indicators,postoperative indicators,postoperative complications and 5-year survival rate were compared among the three groups.Result The intraoperative blood loss,chest drainage time,numerical rating scale(NRS)score and postoperative hospitalization time in the cVATS group and VAMT group were both significantly lower than those in the traditional thoracotomy group(P<0.05).The NRS score,chest drainage time and postoperative hospitalization time in the cVATS group were significantly lower than those in the VAMT group(P<0.05).The overall complications in cVATS group and VAMT group were both significantly lower than those in the traditional thoracotomy group(P<0.05).There was no significant difference in the 5-year survival rate among the three groups(P>0.05).Conclusion The cVATS,VAMT and traditional thoracotomy have no significant effect on 5-year survival rate of patients with lung cancer.The cVATS and VAMT can reduce intraoperative blood loss,chest drainage time,postoperative hospitalization time and postoperative complications compared with traditional thoracotomy.

关 键 词：全胸腔镜手术 胸腔镜辅助小切口手术 传统开胸手术 肺癌 生存率 并发症 

分 类 号：R734.2[医药卫生—肿瘤]