CT靶扫描联合多平面重组对肺部单发微小磨玻璃结节的诊断价值  

Diagnostic value of CT targeted scanning combined with multiple plance reconstruction in single pulmonary ground-glass micro-nodules

作　　者：廖雪燕 刘金凯 吴景强 许凯华 谢鉴津 黄玲玲 Liao Xueyan;Liu Jinkai;Wu Jingqiang;Xu Kaihua;Xie Jianjin;Huang Lingling(Department of Radiology,Longyan First Hospital Affiliated to Fujian Medical University,Fujian 364000,China)

机构地区：[1]福建医科大学附属龙岩第一医院放射科,364000

出　　处：《实用医学影像杂志》2020年第6期597-600,共4页Journal of Practical Medical Imaging

基　　金：福建省临床重点专科建设项目(闽卫医政函〔2018〕145号)。

摘　　要：目的探讨采用CT靶扫描联合多平面重组对于肺部单发微小磨玻璃结节的诊断价值。方法选取我院2018—2019年肺部单发微小磨玻璃结节(micro-GGN)的同时行常规CT及高分辨率靶结节CT检查患者135例,用双盲法对结节的形态特征进行回顾性分析。结果靶扫描联合多平面重组扫描优于常规扫描,差异具有统计学意义(P<0.01)。靶扫描联合多平面重组在显示磨玻璃结节的内部特征(血管征、支气管征、密度),结节直径、结节界面(分叶、毛刺、胸膜凹陷)在浸润前病变与浸润性病变2组之间差异具有统计意义(P<0.01)。Logistic多因素回归分析示血管征及毛刺征为预测微小磨玻璃结节良恶性的独立影响因素(P<0.05)。受试者工作特征曲线(ROC)分析示血管征的曲线下面积为0.845,敏感度为87.0%,特异度为82.0%。毛刺征的曲线下面积为0.784,敏感度为80.4%,特异度为76.4%。结论CT靶扫描联合多平面重组,对于肺部单发微小磨玻璃结节具有较高的诊断价值。血管征及毛刺征在预测肺结节良恶性方面具有重要意义。Objective To investigate the diagnostic value of CT targeted scanning combined with multiple plane reconstruction(MRP)in single pulmonary ground-glass micro-nodules(micro-GGN).Methods One hundred and thirty-five patients with single pulmonary micro-GGN who received the examination of conventional CT scanning and targeted scanning were acquired from our hospital between 2018 to 2019.The morphological characteristics of the nodules were analyzed retrospectively by double-blind method.Results Targeted scanning combined with MPR was superior to conventional scanning,which demonstrated a statistically significant difference(P<0.01).In additional,target scanning combined with MPR displayed statistical significance in showing the internal features(vascular sign,bronchial sign,density)of the nodules,the GGN size and the tumor-lung interface(lobulation,burr and pleural depression signs)between pre-invasion group and invasive adenocarcinoma group(P<0.01).Logistic multivariate regression analysis showed that the vascular sign and the burr sign might be the independent factors for predicting the benign and malignantmicro-GGN(P<0.05).ROC analysis indicated that the curve area sunder the vascular sign and the burr sign were 0.845(sensitivity,87.0%;specificity,82.0%)and 0.784(sensitivity,80.4%;specificity,76.4%)respectively.Conclusion CT targeted scanning combined with MPR has high value for the diagnosis of single pulmonary micro-GGN.The vascular sign and the burr sign might play an important role in predicting the benign and malignantmicro-GGN.

关 键 词：孤立性肺结节 微小磨玻璃结节 体层摄影术 螺旋计算机 病理学 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]