颞下窝良性肿瘤患者术后生活质量的评估以及影响因素的回顾性研究  

Assessment of quality of life of infratemporal fossa benign tumors and analysis of the related influencing factors

作　　者：韩新玲 王振霖[2] 张云云[3] 张秋航 HAN Xinling;WANG Zhenlin;ZHANG Yunyun;ZHANG Qiuhang(Department of Allergy,Beijing Tongren Hospital,Capital Medical University,Beijing,100730,China;Department of Otolaryngology Head and Neck Surgery,Xuanwu Hospital,Capital Medical University,Beijing,100050,China;Department of Otolaryngology Head and Neck Surgery,Tsinghua Changgung Hospital,Tsinghua University,Beijing,102218,China)

机构地区：[1]首都医科大学附属北京同仁医院鼻过敏科,北京100730 [2]首都医科大学宣武医院耳鼻咽喉头颈外科,北京100050 [3]清华大学附属北京清华长庚医院耳鼻咽喉头颈外科,北京102218

出　　处：《中国耳鼻咽喉头颈外科》2020年第11期611-614,共4页Chinese Archives of Otolaryngology-Head and Neck Surgery

基　　金：国家自然科学基金面上项目(81170894)。

摘　　要：目的评估颞下窝良性肿瘤患者手术前后的生活质量状况,分析生活质量相关影响因素。方法应用头颈部癌症治疗功能评估调查问卷(the Functional Assessment of Cancer Therapy-Head and Neck,FACT-H&N)中文版与鼻腔鼻窦结局测试22条(Sinonasal Outcome Test-22,SNOT-22)中文版,对首都医科大学宣武医院耳鼻咽喉头颈外科2010年1月~2016年8月收治的58例颞下窝良性肿瘤患者手术治疗前后的生活质量(quality of life,QOL),以及其中31例内镜经鼻入路患者手术前后鼻腔鼻窦功能状况进行评估,应用MS Excel、SPSS 22.0进行统计分析。结果颞下窝良性肿瘤患者术后总体QOL以及身体、情感、功能状况均好于术前,头颈部功能状况可能较术前差。年龄、手术方式以及病理类型是颞下窝良性肿瘤患者QOL的影响因素,经鼻内镜手术入路患者术后鼻腔鼻窦功能优于术前。结论手术治疗有助于提高颞下窝良性肿瘤患者的远期QOL,内镜经鼻入路较开放式入路更能给患者带来身体、情感、头颈部功能状况方面的获益且内镜经鼻入路可改善患者远期鼻腔鼻窦功能状况。OBJECTIVE To evaluate the patients’QOL before and after the resection of infratemporal fossa benign tumors,ascertain and analyze the relevant influencing factors.METHODS A retrospective study was conducted on assessing the patients’quality of life by using the Chinese version of the Functional Assessment of Cancer Therapy-Head and Neck Questionnaire(FACT-H&N)and Sinonasal Outcome Test-22 Questionnaire(SNOT-22).A total of 58 patients who had infratemporal fossa benign tumors and undergone surgery in the ENT Department in Xuanwu Hospital from January 2010 to August 2016 were included,meanwhile the sinonasal status 31 patients who had endoscopic endonasl surgery were also evaluated.We used MS Excel and SPSS 22.0 to perform statistical analysis.RESULTS The general QOL,and the physical,emotional,functional domains(P=0.000,P=0.000,P=0.048,P=0.000,P=0.000)were all improved compared with pre-operation,while the H&N domain might getting worse(P=0.009).Age,surgery approach,and pathological type were the potential influencing factors of the QOL(P=0.009,P=0.021,P=0.001).The sinonasal functional status of those who had endoscopic endonasal surgery was improved after the operation(P=0.012).CONCLUSION Surgical treatment can help the patients with infratemporal fossa benign tumors to improve their long-term QOL,physically,emotionally,functionally,and generally.Endoscopic technology,especially endonasal approach can possess patients with better physical,emotional,H&N functional status compared with open surgery.Meanwhile,it also improves patients’long-term sinonasal function status.

关 键 词：头颈部肿瘤 生活质量 问卷调查 外科手术 颞下窝 

分 类 号：R739.91[医药卫生—肿瘤]