生长激素联合早期肠内营养治疗重症急性胰腺炎的临床效果  

Clinical efficacy of growth hormone combined with early enteral nutrition in treating severe acute pancreatitis

作　　者：张彦亭[1] 庄坤[1] 原姗姗[1] 刘家铭 杨振威[1] ZHANG Yanting;ZHUANG Kun;YUAN Shanshan;LIU Jiaming;YANG Zhenwei(Department of Gastroenterology,Xi′an Central Hospital,Xi′an,Shaanxi 710000,China)

机构地区：[1]陕西省西安市中心医院消化内科,陕西西安710000

出　　处：《检验医学与临床》2021年第1期73-75,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨生长激素联合早期肠内营养治疗重症急性胰腺炎的临床效果。方法选取该院2018年1月至2019年12月收治的100例重症急性胰腺炎患者,根据数字随机表法分为对照组和观察组,每组50例。两组均给予常规治疗,对照组在常规治疗的基础上联合生长激素治疗,观察组在对照组的基础上联合早期肠内营养治疗,比较两组应用效果。结果对照组总有效率84.00%,观察组总有效率96.00%,观察组高于对照组(P<0.05)。观察组腹痛缓解时间、血淀粉酶恢复正常时间、住院时间均少于对照组(P<0.05)。治疗后,两组血清清蛋白(ALB)和总蛋白(TP)水平均高于治疗前,且观察组均高于对照组(P<0.05)。结论生长激素联合早期肠内营养治疗的应用,对重症急性胰腺炎患者效果明显,可促进相关症状的快速缓解和恢复,以及营养状况的改善。Objective To investigate the clinical efficacy of growth hormone plus early enteral nutrition in the treatment of severe acute pancreatitis.Methods A total of 100 patients with severe acute pancreatitis admitted to this hospital from January 2018 to December 2019 were selected and divided into the control group and observation group according to the random number table method,50 cases in each group.Both groups were given the conventional treatment.The control group was combined with growth hormone therapy on the basis of conventional treatment,while the observation group was combined with the early enteral nutrition therapy on the basis of the control group.Then the effects were compared between the two groups.Results The total effective rate in the control group was 84.00%,which in the observation group was 96.00%,and the observation group was higher than the control group(P<0.05).The abdominal pain relief time,time of blood amylase recovery to normal and the hospitalization stay in the observation group all were shorter than those in the control group(P<0.05).After treatment,serum ALB and TP levels in both groups were higher than those before treatment,moreover the observation group was higher than the control group(P<0.05).Conclusion The application of growth hormone combined with early enteral nutrition therapy has obvious effect on the patients with severe acute pancreatitis,which can promote the rapid relief and recovery of related symptoms and the improvement of nutritional status.

关 键 词：急性胰腺炎 生长激素 早期肠内营养 血淀粉酶 清蛋白 

分 类 号：R576[医药卫生—消化系统]