直接加间接颅内外血管重建术对成人缺血型烟雾病患者认知功能改善的研究  

Benifits for Cognitive deficits of direct and indirect revascularization surgery for adult patients with ischemic moyamoya disease

作　　者：袁小威 吴建珩[1] 王振[1] YUAN Xiao-wei;WU Jian-heng;WANG Zhen(The Fifth Affiliated Hospital of Zhengzhou University,Henan Zhengzhou 450000,China)

机构地区：[1]郑州大学第五附属医院,河南郑州450000

出　　处：《临床医药文献电子杂志》2020年第86期4-5,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的探讨直接加间接颅内外血管重建术对成人缺血型烟雾病患者认知功能的改善作用。方法选取75例行颅内外直接加间接血管重建术的伴有不同程度认知功能障碍的缺血型成人烟雾病患者,分别在术前、术后6个月以及术后1年三个时间点应用简易精神状态检查量表(MMSE)。术后6个月复查患者脑血管造影(DSA)观察患者颅内血液循环情况。结果术后6个月及术后1年MMSE总分明显提高(P<0.05);术后6个月复查患者DSA,75例(100%)患者脑底异常血管网均较术前显著减少,并且存在新生的侧支血管。结论直接加间接颅内外血管重建术可以明显改善成人缺血型烟雾病患者的认知障碍。Objective To disscuss the Benifits for Cognitive deficits of direct and indirect revascularization surgery for adult patients with ischemic moyamoya disease.Methods A group of 75 adult patients with ischemic moyamoya disease that underwent direct and indirect revascularization surgery was studied.Use Minimentalstateexamination(MMSE)to evaluate cognitive deficits before,6 months and 1 year after the surgery.USE DSA to evaluate the cerebral blood flow 6 months after the surgery.Results Scores of mini-mentalstateexamination(MMSE)when 6 months and 1 year after the surgery enhanced compared wiht the scores before the surgery(P<0.05).The cerebral blood flow improved in all patients on DSA.Conclusions Direct and indirect revascularization surgery for adult patients with ischemic moyamoya disease can enhance cognitive function.

关 键 词：烟雾病 手术 认知障碍 

分 类 号：R743[医药卫生—神经病学与精神病学]