骨盆尤文肉瘤治疗的研究进展  

Research progress on the treatment of pelvis Ewing’s sarcoma

作　　者：穆浩然 左冬青 蔡郑东 MU Hao-ran;ZUO Dong-qing;CAJ Zhengdong(Department of Orthopaedics,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai,200080,China)

机构地区：[1]上海交通大学医学院,200080 [2]上海市第一人民医院骨科,200080

出　　处：《中国骨与关节杂志》2020年第12期908-912,共5页Chinese Journal of Bone and Joint

基　　金：国家自然科学基金(81802985)。

摘　　要：尤文肉瘤(Ewing’s sarcoma)是一种常见于儿童和青少年的恶性肿瘤。1921年,由Ewing最先报道。尤文肉瘤患者的平均年龄为15岁,发病率约为2.93/百万人,占原发骨肿瘤的16%,与骨肉瘤、软骨肉瘤一起被称为三种最常见的骨肿瘤[1]。尤文肉瘤的起源尚不清楚,根据目前的研究,尤文肉瘤被归类为"尤文肉瘤家族"(Ewing’s sarcoma family of tumors,ESFT)[2]。Ewing’s sarcoma is usually found in the pelvis of children and young adults,accounting for20%-30%of the total.Surgery and radiotherapy are recommended to remove and control the lesion based on systemic chemotherapy.The overall survival rate of Ewing’s sarcoma has been increased,but there are still some factors that make the poor prognosis at the pelvis.The Ewing’s sarcoma found at the pelvis often has a large volume,and surrounding tissues and organs are sensitive to radiation.Complications after pelvis rebuild affect the survival rate and prognosis,so that it is still challenging based on improved or new treatment methods.Therefore,we conclude the achievements of pelvis Ewing’s sarcoma treatment to provide references for further researches.

关 键 词：EWING肉瘤 骨盆 骨肿瘤 治疗 综述 

分 类 号：R738.1[医药卫生—肿瘤]