基底细胞癌诊断及治疗研究进展  

Research Progress in Diagnosis and Treatment of Basal Cell Carcinoma

作　　者：张艳(综述)[1,2] 范星(审校) Zhang Yan;Fan Xing(Department of Dermatology,the First Affiliated Hospital of Anhui Medical University,Hefei 230032,Anhui,China;Institute of Dermatology,Anhui Medical University,Hefei 230022,Anhui,China)

机构地区：[1]安徽医科大学第一附属医院皮肤科,合肥230032 [2]安徽医科大学皮肤病研究所,合肥230022

出　　处：《肿瘤预防与治疗》2020年第12期943-948,共6页Journal of Cancer Control And Treatment

基　　金：认知智能国家重点实验室(科大讯飞)开放研究基金(编号:COGOSC-20190001)。

摘　　要：基底细胞癌(basal cell carcinoma,BCC)是来自基底细胞层的恶性肿瘤,它与紫外线照射有着密切的关系,因此颜面部为BCC的好发部位。组织病理学检查是诊断BCC的金标准。BCC早期病变根据临床特点很容易被误诊,近年来随着皮肤影像学技术的发展,非侵入性诊断工具,如皮肤镜、反射式共聚焦显微镜、高频超声等的应用,让更多的早期BCC被发现,从而减少了良性皮肤病变的活检次数。治疗方案的选择主要依据肿瘤的组织病理学类型、大小、部位以及浸润程度所决定,手术切除为目前最主要的治疗手段,除此之外,化疗、药物、光动力、放疗、电灼术、冷冻、激光消融及联合治疗也是较常用的方法。Basal cell carcinoma(BCC) is a malignant tumor from the basal cell layer, which is closely related to ultraviolet irradiation. Therefore, face is a common site of BCC. The clinical characteristics of early BCC are easily misdiagnosed. The diagnosis of BCC is mainly based on histopathology. Fortunately, with the development of skin imaging technology, BCC can be more early discovered by non-invasive diagnostic tools, such as dermoscopy, reflectance confocal microscopy, high frequency ultrasound and so on, thus reducing the number of biopsies of benign skin lesions. The choice of treatment is mainly determined by the histopathological type, size, location and degree of invasion of the tumor. Surgical resection is the most important treatment at present. In addition, chemotherapy, medication, photodynamic therapy, radiotherapy, electrocautery, liquid nitrogen freezing, laser ablation and combined therapy are also commonly used.

关 键 词：基底细胞癌 诊断方法 治疗 

分 类 号：R739.5[医药卫生—肿瘤]