结肠腺瘤性息肉与非腺瘤性息肉的临床特征比较  

Comparison of clinical features between colon adenomatous polyps and non-ade⁃nomatous polyps

作　　者：张莉[1] 王李心 高旭东 王国芬 李英茹[1] 盛丽荣 陈希琳[1] Zhang Li;Wang Lixin;Gao Xudong;Wang Guofen;Li Yingru;Sheng Lirong;Chen Xilin(Department of Endoscopy,Beijing Er Long Lu Hospital,Beijing 100120,China)

机构地区：[1]北京市二龙路医院内镜室,北京100120

出　　处：《结直肠肛门外科》2020年第6期710-712,共3页Journal of Colorectal & Anal Surgery

摘　　要：目的分析结肠腺瘤性息肉与非腺瘤性息肉的临床特征差异。方法回顾性分析2017年1月至2019年1月本院收治的356例结肠息肉患者临床资料,按病理类型的不同分为腺瘤性息肉组(n=208)和非腺瘤性息肉组(n=148),比较两组一般资料、生化指标、息肉大小及检出部位的差异。结果腺瘤性息肉组男性、有吸烟史、合并2型糖尿病患者的比例高于非腺瘤性息肉组,腺瘤性息肉组平均年龄更大、BMI更高(均P<0.05);两组饮酒史比较差异无统计学意义(P>0.05)。两组ALT、AST、Scr、TC、TG、LDL-C、HDL-C水平比较,差异均无统计学意义(均P>0.05);腺瘤性息肉组UA、FBG、F-ins、空腹C-肽及HbA1c水平高于非腺瘤性息肉组(均P<0.05)。两组息肉大小、检出部位比较,差异均无统计学意义(均P>0.05)。结论结肠腺瘤性息肉患者中男性、吸烟、合并2型糖尿病的患者比例高于非腺瘤性息肉患者,前者平均年龄更大、BMI更高。关于生活习惯、代谢水平与结肠腺瘤性息肉发生的关系还需要更为深入的探讨与分析。Objectives To compare the clinical features between colon adenomatous polyps and non-adenomatous polyps.Methods This was a retrospective analysis of 356 patients with colon polyps treated in our hospital between January 2017 and Janu⁃ary 2019.Patients were divided into adenomatous polyp group(n=208)and non-adenomatous polyp group(n=148)depending on the pathological types.General characteristics,biochemical characteristics,polyp size,and location were compared between the two groups.Results The adenomatous polyp group was with older average age and higher BMI and had significantly higher pro⁃portions of men,smoking history,and concomitant type 2 diabetes mellitus than the non-adenomatous polyp group(P<0.05).The two groups were comparable in drinking habits and the levels of alanine transaminase,aspartate transaminase,serum creatinine,total cholesterol,triglyceride,low-density lipoprotein cholesterol,and high-density lipoprotein cholesterol levels(P>0.05).The uric acid levels,fasting blood glucose,fasting insulin,fasting connective peptide,and HbA1c were higher in the adenomatous polyp group(P<0.05).Polyp size and location were comparable between the two groups(P>0.05).Conclusion Patients with adenoma⁃tous polyp are more likely to be men,smokers,concomitant type 2 diabetes mellitus,and with older age and higher BMI than those with the non-adenomatous polyp.More research was needed to investigate the risk of colon adenomatous polyps in terms of lifestyle and metabolism.

关 键 词：结肠息肉 腺瘤性息肉 非腺瘤性息肉 临床特征 

分 类 号：R735.34[医药卫生—肿瘤]