宫颈癌术后并发医院感染的病原菌检测及影响因素分析  

Detection and influencing factors of nosocomial infection after cervical cancer surgery

作　　者：邢利 郑媛[1] 陈丰华[1] 王浩[1] 施宝美[1] 冯晓萍 金玲玲 XING Li;ZHENG Yuan;CHEN Fenghua;WANG Hao;SHI Baomei;FENG Xiaoping;JIN Lingling(Department of Gynecology, Yiwu Central Hospital, Yiwu 322000, China)

机构地区：[1]义乌市中心医院妇科,浙江义乌322000

出　　处：《健康研究》2020年第6期704-706,共3页Health Research

摘　　要：目的检测宫颈癌根治术后患者并发医院感染的病原菌,并分析导致术后感染的影响因素。方法宫颈癌根治术患者按照术后是否发生医院病原菌感染分为感染组和未感染组,检测并统计患者的医院感染情况,比较2组患者的临床资料,多因素Logistic回归分析影响宫颈癌术后并发医院感染的危险因素。结果80例宫颈癌手术治疗患者共发生医院感染21例,感染率为26.25%。分离出病原菌26株,其中革兰阴性菌15株(占57.69%),以大肠埃希菌为主;革兰阳性菌9株(占34.62%),以金黄色葡萄球菌为主;真菌2株(占7.69%)。2组患者的年龄、糖尿病史、贫血、手术时间、住院时间以及是否化疗差异有统计学意义(P<0.05),年龄大、合并糖尿病、手术时间与住院时间长以及接受化疗为宫颈癌术后并发医院感染的独立危险因素(P<0.05)。结论为减少宫颈癌术后医院感染率,需重点关注60岁以上、合并糖尿病、手术时间与住院时间长以及接受化疗的患者。Objective To detect and analyze the influencing factors of the pathogens of nosocomial infection after cervical cancer radical surgery.Methods Patients with cervical cancer who underwent radical operation were divided into the infection group and the non-infection group based on the positive nosocomial infection or not.The clinical characteristics and risk factors of nosocomial infection after cervical cancer surgery were analyzed by using multivariate Logistic regression.Results A total of 21 nosocomial infections(26.25%)occurred in 80 patients after cervical cancer radical surgery.Twenty-six strains of pathogenic bacteria were isolated,including 15 Gram-negative bacteria(57.69%),mainly Escherichia coli,nine Gram-positive bacteria(34.62%),predominantly Staphylococcus aureus and two fungi(7.69%).There was a statistically significant difference between the two groups in terms of age,history of diabetes,anemia,duration of surgery,length of hospital stay,and chemotherapy(P<0.05).Age,combined diabetes,length of operation and hospitalization,and chemotherapy were the independent risk factors for nosocomial infection after cervical cancer surgery(P<0.05).Conclusions In order to reduce the nosocomial infection rate after the operation of cervical cancer,it is necessary to focus on the patients who were either more than 60 years old,combined diabetes,longer operation time and hospitalization or underwent chemotherapy.

关 键 词：宫颈癌 医院感染 手术 病原菌 

分 类 号：R737.33[医药卫生—肿瘤]