Neuro-Endoport技术辅助神经内镜治疗脑室内肿瘤的临床疗效  

Clinical efficacy of neuroendoscopic treatment of intraventricular tumors assisted with Neuro-Endoport technology

作　　者：聂丁 程建华 李斌[2] 应建有 李储忠[2] 桂松柏[1] 王新生[1] 张亚卓[2] 赵澎[1] Nie Ding;Cheng Jianhua;Li Bin;Ying Jianyou;Li Chuzhong;Gui Songbai;Wang Xinsheng;Zhang Yazhuo;Zhao Peng(Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Beijing Institute of Neurosurgery,Capital Medical University,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院神经外科,100070 [2]首都医科大学,北京市神经外科研究所,100070

出　　处：《中华神经外科杂志》2020年第12期1236-1240,共5页Chinese Journal of Neurosurgery

基　　金：首都医科大学校培育基金(PYZ19115)。

摘　　要：目的观察Neuro-Endoport技术辅助神经内镜治疗脑室内肿瘤的临床效果。方法回顾性分析2018年1月至2019年12月首都医科大学附属北京天坛医院神经外科采用Neuro-Endoport技术辅助神经内镜治疗脑室内肿瘤患者的临床资料,共15例。观察其手术时间、肿瘤切除程度、术中出血量、术后并发症及随访结果。结果15例患者中,肿瘤全切除12例,近全切除3例。手术时间为2.5~7.0(4.2±1.6)h,术中出血量为100~1000(352±73)ml;术中造瘘10例;术中均无并发症发生。住院天数为8~20(12.3±4.3)d;术后发生颅内感染2例、脑水肿4例、癫痫发作2例、脑积水1例。15例患者的随访时间为3~12(7.9±2.3)个月。随访期间10例术前合并脑积水的患者症状明显缓解,2例癫痫发作者未再发作,4例脑水肿和2例颅内感染者均恢复良好;头颅MRI显示,10例造瘘患者的脑室均不同程度地缩小,4例未行造瘘的患者未出现明显脑积水,1例术后脑积水患者的脑室较出院前缩小。所有患者的肿瘤均无复发。结论Neuro-Endoport技术辅助神经内镜手术治疗脑室内肿瘤术中并发症发生率低,术后疗效好。Objective To explore the efficacy of neuroendoscopic treatment of intraventricular tumors assisted with Neuro-Endoport technology.Methods A retrospective study was conducted on the clinical data of 15 patients with intraventricular tumors who underwent neuroendoscopic treatment assisted with Neuro-Endoport technology from January 2018 to December 2019 at Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University.We documented the operation duration,tumor resection degree,intraoperative blood loss,postoperative complications and follow-up results.Results Of the 15 patients,12 had total tumor resection and 3 had near-total resection.The operation duration was 2.5-7.0(4.2±1.6)hours,and intraoperative blood loss was 100-1000(352±73)ml.Ventriculostomy was performed during operation in 10 cases.No intraoperative complications occurred.The length of hospital stay was 8-20(12.3±4.3)days.There were two cases of intracranial infection,four cases of cerebral edema,two cases of seizures,and one case of hydrocephalus after operation.The follow-up duration of 15 patients was 3-12(8±2)months.During the follow-up period,the symptoms of 10 patients with preoperative hydrocephalus were significantly relieved;two patients with previous seizures did not report new events of seizures;four patients with cerebral edema and two patients with intracranial infection recovered well;head MRI showed that the ventricles of 10 patients with ventriculostomy shrank to varying degrees,four patients without ventriculostomy showed no obvious hydrocephalus,and one patient with postoperative hydrocephalus had a smaller ventricle than that before discharge.None of the patients had tumor recurrence.Conclusion Neuroendoscopic surgery assisted with Neuro-Endoport technology seems safe and effective for the treatment of intraventricular tumors.

关 键 词：自然腔道内镜手术 脑室肿瘤 Neuro-Endoport技术 治疗结果 

分 类 号：R739.41[医药卫生—肿瘤]