Asymmetric dimethylarginine-induced oxidative damage leads to cerebrovascular dysfunction  

作　　者：Mushfiquddin Khan Inderjit Singh Jeseong Won 

机构地区：[1]Children’s Research Institute,Medical University of South Carolina,Charleston,SC,USA

出　　处：《Neural Regeneration Research》2021年第9期1793-1794,共2页中国神经再生研究（英文版）

基　　金：supported by the State of South Carolina Spinal Cord Injury Research Fund Board grant No.SCIRF#2017(to MK);the NIH grant No.R21NS114433(to JW and MK);the U.S.Department of Veterans Affairs grant No.RX002090(to IS)。

摘　　要：Asymmetric dimethylarginine(ADMA) and its enantiomer, symmetric dimethylarginine(SDMA), are naturally-occurring methylated metabolites of the L-arginine amino acid moiety of proteins followed by proteolysis(Grosse et al., 2020). These metabolites were first identified in human urine in 1970.

关 键 词：OXIDATIVE MOIETY SYMMETRIC 

分 类 号：R743[医药卫生—神经病学与精神病学]