降钙素原在急性胰腺炎及胰腺感染中的价值  

The value of procalcitonin in acute pancreatitis and pancreatic infection

作　　者：马进坡 徐德全[1] 赵加斌[1] 周昊昕[1] 侯利民[1] MA Jinpo;XU Dequan;ZHAO Jiabin;ZHOU Haoxin;HOU Limin(Department of Emergency Surgery,The First Affiliated Hospital,Harbin Medical University,Harbin 150001,P.R.China)

机构地区：[1]哈尔滨医科大学附属第一医院急诊外科,哈尔滨150001

出　　处：《中国普外基础与临床杂志》2021年第1期130-134,共5页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的总结降钙素原(PCT)在急性胰腺炎的早期严重程度预测、治疗效果评价、预后评估及抗生素使用中的临床价值。方法检索近年来国内外有关重症急性胰腺炎及胰腺感染坏死的血液学指标的文献并进行综述。结果PCT在诊断重症急性胰腺炎的发生和胰腺感染坏死中具有较高的灵敏度和特异度,可以作为指导重症急性胰腺炎的早期临床治疗的工具。在重症急性胰腺炎的治疗过程中,随着病情的好转,PCT值是下降的,监测PCT值的变化不仅可以评价重症急性胰腺炎的治疗效果,还可以规范抗生素的使用。结论PCT可当作预测重症急性胰腺炎和胰腺感染坏死发生的早期指标,还可作为指导抗生素治疗的指标。Objective To summarize the clinical value of procalcitonin(PCT)in the prediction of early stage of acute pancreatitis,the evaluation of therapeutic effect,the evaluation of prognosis,and the use of antibiotics.Method We reviewed the related literatures about hematology indexes of severe acute pancreatitis and pancreatic infection and necrosis at home and abroad in recent years.Results PCT had high sensitivity and specificity in the diagnosis of severe acute pancreatitis and pancreatic infection and necrosis,and could be used as a tool to guide the early clinical treatment of severe acute pancreatitis.In the course of treatment,with the improvement of the condition,the value of PCT decreased.Monitoring the change of PCT value could evaluate the therapeutic effect of severe acute pancreatitis.Monitoring PCT during treatment could also guide the use of antibiotics.Conclusion PCT can be used as an early indicator for predicting severe acute pancreatitis and necrosis of pancreatic infection,as well as an indicator for guiding antibiotic treatment.

关 键 词：降钙素原 重症急性胰腺炎 急性胰腺炎 胰腺感染坏死 综述 

分 类 号：R576[医药卫生—消化系统]