上消化道同时性重复癌116例临床特征  

Clinical features of 116 cases of simultaneous repeated cancer of upper digestive tract

作　　者：刘金殿 吴正奇 张志镒 卢林芝 赵光源 李世华 秦天燕 LIU Jin-dian;WU Zheng-qi;ZHANG Zhi-yi;LU Lin-zhi;ZHAO Guang-yuan;LI Shi-hua;QIN Tian-yan(Digestive Department of Wuwei Cancer Hospital,Wuivei 733000,P.R.China)

机构地区：[1]武威肿瘤医院消化科,甘肃武威733000

出　　处：《中华肿瘤防治杂志》2020年第22期1821-1826,共6页Chinese Journal of Cancer Prevention and Treatment

基　　金：国家重点研发计划(2017YFC0908302)。

摘　　要：目的探讨上消化道同时性重复癌的相关临床病理特征,为临床工作中上消化道同时性重复癌的诊断提供参考。方法收集2015-08-01-2019-03-31甘肃省武威肿瘤医院通过内镜及病理确诊的116例上消化道同时性重复癌患者的临床病理资料,通过回顾性分析方法,采用中位数和极差以及构成比等指标对病例资料进行统计描述,分析上消化道同时性重复癌的临床特征。结果116例上消化道同时性重复癌中男女性别比为6.7∶1,年龄30~88岁,平均年龄(63.52±8.96)岁。同时性重复癌的癌灶在食管的好发部位遵循单发食管癌的好发部位,早期癌占62.3%(66/106),内镜下分型以0~Ⅱ型为主,病灶平均长径为2.5cm,病理类型以分化型癌和原位癌为主;进展期癌灶的内镜分型以髓质型和溃疡型为主,平均长径为4.5cm,病理类型以未分化癌为主。癌灶在胃的除8例BorrmanⅣ型病变外,胃角口侧以上的癌灶占74.2%(92/124)。其中早期癌占34.8%(46/132),0~Ⅱ型癌灶占63.0%(29/46),平均长径为1.5cm,原位癌和未分化癌共占54.3%(25/46);进展期癌灶中,有70.5%(55/78)的癌灶分布于胃角口侧以上,BorrmannⅡ和Ⅲ型共占82.0%(64/78),1.0~9.0cm,平均长径为4.0cm。病理类型未分化癌占83.7%(72/86)。结论上消化道重复癌病灶以早期肿瘤为主,在今后的临床工作中重视上消化道同时性重复癌的诊断,做到早期诊断和积极综合治疗,以延长患者的生存期,改善预后。OBJECTIVE To explore the relevant clinicopathological characteristics of simultaneous repetitive upper gastrointestinal cancer,and provide reference for the diagnosis of upper gastrointestinal repetitive cancer in clinical work.METHODS The clinicopathological data of 116 patients with synchronous repetitive upper gastrointestinal cancer diagnosed through endoscopy and pathology at Wuwei Cancer Hospital from August 1,2015 to March 31,2019 were collected.Indexes such as median,range and constituent ratio were used to statistically describe the clinical data,and analyze the clinical features of synchronous repetitive upper gastrointestinal cancer.RESULTS The sex ratio of male to female in116 cases of synchronous repetitive upper gastrointestinal cancer was 6.7∶1,and the age of detection was between 30 and88,and the average age was(63.52±8.96).The cancer foci of synchronous repetitive cancer in the most common esophageal site followed the most common site of single esophageal cancer.Early-stage cancer accounted for 62.3%(66/106).The endoscopic classification was mainly type 0-Ⅱ,with a size of 2.5 cm,the pathological type was mainly differentiated carcinoma and carcinoma in situ.The endoscopic type of advanced cancer was mainly medullary type and ulcer type,the size was 4.5 cm,and the pathological type was mainly undifferentiated carcinoma.Except for 8 cases of Borrman typeⅣlesions with cancer in the stomach,74.2%(92/124)of cancers above the mouth side of the gastric angle accounted for.Among them,early cancer accounted for 34.8%(46/132),type 0-Ⅱcancer lesions accounted for 63.0%(29/46),with a size of 1.5 cm,and carcinoma in situ and undifferentiated carcinoma accounted for 54.3%(25/46).Among the advanced cancer foci,70.5%(55/78)of the cancer foci were located above the mouth side of the gastric angle,Borrmann typeⅡBorrmann typeⅢaccounted for 82.0%(64/78),the diameter was 1.0 to 9.0 cm,and the average size was 4.0 cm.Pathological types of undifferentiated cancer accounted for 83.7%(72/86).CONCLUSIONS The

关 键 词：上消化道 同时性重复癌 临床特征 

分 类 号：R735[医药卫生—肿瘤]