鼻咽癌螺旋断层放疗与固定野静态调强放疗的剂量学比较  

Dosimetric Comparison between Spiral Tomography Radiotherapy and Fixed-fi eld Static Intensity-modulated Radiotherapy for Nasopharyngeal Carcinoma

作　　者：徐露 蔡汉飞[1] 方美芳 蔡丰[1] XU Lu;CAI Han-fei;FANG Mei-fang;CAI Feng(The First Affi liated Hospital of Bengbu Medical College,Anhui Bengbu 233000)

机构地区：[1]蚌埠医学院第一附属医院,安徽蚌埠233000

出　　处：《深圳中西医结合杂志》2020年第23期7-8,共2页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

基　　金：蚌埠医学院自然科学基金面上项目资助课题(BYKY17111)。

摘　　要：目的:比较鼻咽癌螺旋断层放疗(TOMO)与固定野静态调强放疗(IMRT)的剂量学指标。方法:选择蚌埠医学院第一附属医院2018年1月至2019年12月期间收治的80例鼻咽癌患者,按照随机数字法分为两组,各40例。观察组给予TOMO处理,对照组给予IMRT处理。比较两组靶区剂量、危及器官剂量。结果:观察组患者肿瘤靶区、颈部转移淋巴结、亚临床病灶及预防照射区D95剂量低于对照组,差异具有统计学意义(P<0.05)。观察组危及脑干、脊髓、视交叉剂量显著低于对照组,差异具有统计学意义(P<0.05)。结论:观察组与对照组均能用于临床,但观察组在放疗中的剂量分布优势更明显,危及器官剂量更低,能更好地保护正常组织。Objective To compare the dosimetric indexes between spiral tomography radiotherapy and static intensity modulated radiotherapy in fi xed fi eld for nasopharyngeal carcinoma. Methods 80 cases with nasopharyngeal carcinoma admitted to the first affiliated hospital of Bengbu medical college from January 2018 to December 2019 were randomly divided into two groups, 40 cases each. The target dose and organ-threatening dose were compared between the two groups. Results The d95 of TOMO gross tumor volume (PGTVnx), cervical metastatic lymph nodes (PGTVnd), subclinical lesions (PTV1) and radiation prevention area (PTV2) were signifi cantly lower than those of IMRT (P < 0.05), and the dose of Tomo endangering brain stem was signifi cantly lower than that of IMRT (P < 0.05). Conclusion The plans of Tomotherapy group and intensity-modulated group can be used in clinic, but Tomotherapy group has more obvious advantages in dose distribution in radiotherapy, lower dose of endangered organs and better protection of normal tissues.

关 键 词：鼻咽癌 螺旋断层放疗 固定野静态调强放疗 

分 类 号：R739.6[医药卫生—肿瘤]