急进高原官兵左心室舒张功能的变化研究  

Changes of left ventricular diastolic function in soldiers rapidly ascending to plateau

作　　者：柴青芬 刘超 姚胜银 宋红玮 王永辉 王圣明 CHAI Qingfen;LIU Chao;YAO Shengyin;SONG Hongwei;Wang Yonghui;WANG Shengming(Department of Ultrasound,NO.988 Hospital of Joint Logistic Support Force,Zhengzhou,Henan 455000,China)

机构地区：[1]中国人民解放军联勤保障部队第九八八医院超声科,郑州455000

出　　处：《重庆医学》2021年第1期84-87,共4页Chongqing medicine

基　　金：河南省科技攻关联合共建项目(LH 20190019)。

摘　　要：目的应用多普勒评价进藏官兵左心室舒张功能。方法对50名急进高原官兵赴高原前和赴高原1个月时进行常规彩色多普勒超声检查,测量左房容积指数(LAVI)、左室射血分数(LVEF)、二尖瓣E峰血流速度(E)、二尖瓣A峰血流速度(A)、二尖瓣瓣口组织多普勒舒张早期速度峰值(e′)、舒张晚期速度峰值(a′)、E/e′比值。结果常规超声显示官兵急进高原后舒张末期右心室横径、主肺动脉内径较赴高原前增大,心率明显增快,心输出量明显增加,差异有统计学意义(P<0.05);与急进高原前相比,急进高原后1个月E/A,e′,e′/a′降低,E/e′,a′升高,差异有统计学意义(P<0.05)。在40岁以上人群E/A,e′,e′/a′,E/e′变化更加明显。结论急进高原后出现早期左心功能异常,为舒张功能异常,40岁以上人群更为明显,可通过E/e′进行评估。Objective To investigate the changes of left ventricular diastolic function in soldiers rapidly ascending to plateau.Methods Routine color Doppler ultrasonography was performed on 50 soldiers rapidly ascending to plateau before and one month after departure to it.Left atrial volume index(LAVI),left ventricular ejection fraction(LVEF),mitral valve peak blood flow velocity(E),mitral valve peak A velocity(A),mitral orifice tissue doppler early diastolic velocity peak(E′),late diastolic velocity peak(A′),E/E′ratio were measured.Results After rapidly ascending to plateau,the inner diameter of the main pulmonary artery increased,the heart rate increased significantly,the cardiac output increased significantly,and the differences were statistically significant(P<0.05).Compared with before rapidly ascending to plateau,E/A,E′,E′/A′decreased,E/e′,A′increased at 1 month after rapidly ascending to plateau,and the differences were statistically significant(P<0.05).In group of age over 40′s,E/A,e′,e′/a′,E/e′were significantly different.Conclusion After rapidly ascending to plateau,early left cardiac dysfunction-diastolic dysfunction appeared,which is more obvious in people over 40 years old,and can be assessed by E/e′.

关 键 词：高原 超声心动图 组织多普勒 左心舒张功能 

分 类 号：R730.41[医药卫生—肿瘤]