Histoplasmosis and inflammatory bowel disease: A case report  

作　　者：Dushyant Dahiya Asim Kichloo Jagmeet Singh Michael Albosta Farah Wani 

机构地区：[1]Internal Medicine,Central Michigan University,Saginaw,MI 48603,United States [2]Internal Medicine,Samaritan Medical Center,Watertown,NY 13601,United States [3]Internal Medicine,Guthrie Robert Packer Hospital,Sayre,PA 18840,United States

出　　处：《World Journal of Gastrointestinal Endoscopy》2021年第1期24-32,共9页世界胃肠内镜杂志（英文版）（电子版）

摘　　要：BACKGROUND Infection with Histoplasma capsulatum can lead to a disseminated disease involving the gastrointestinal tract presenting as diffuse abdominal pain and inflammatory diarrhea which may mimic inflammatory bowel disease(IBD).CASE SUMMARY In the current report,we discuss the case of a 41-year old male who presented to the emergency department with complaints of high-grade intermittent fevers and severe abdominal pain with associated diarrhea and hematochezia.Laboratory results demonstrated transaminitis and elevated erythrocyte sedimentation rate,C-reactive protein and ferritin levels.The patient’s presentation was thought to be an exacerbation of his underlying IBD,but further investigations revealed a positive Histoplasma antigen in the urine.The patient was offered a colonoscopy and biopsy to confirm the diagnosis;however,he refused.He was treated with itraconazole and showed significant improvement of his symptoms,thereby confirming the diagnosis of gastrointestinal histoplasmosis.CONCLUSION Here within,we provide a review of IBD,evaluation of chronic diarrhea,and gastrointestinal histoplasmosis.

关 键 词：HISTOPLASMOSIS Inflammatory bowel disease INTESTINE ENDOSCOPY GASTROENTEROLOGY Case report 

分 类 号：R574[医药卫生—消化系统]